Low and high body mass index in hidradenitis suppurativa patients-different subtypes?

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Low and high body mass index in hidradenitis suppurativa patients-different subtypes? / Theut Riis, P; Saunte, D M; Benhadou, F; Del Marmol, V; Guillem, P; El-Domyati, M; Abdel-Wahab, H; Antoniou, C; Dessinioti, C; Gürer, M A; Beksaç, B; Szepietowski, J C; Matusiak, L; Emtestam, L; Lapins, J; Riad, H; Doss, N; Massa, A F; Hamzavi, I; Nicholson, C; Dolenc-Voljc, M; Kim, K H; Ohn, J; Zouboulis, C C; Karagiannidis, I; Mokos, Z B; Durinec, P; Jemec, G B E.

I: Journal of the European Academy of Dermatology and Venereology : JEADV, Bind 32, Nr. 2, 02.2018, s. 307-312.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Theut Riis, P, Saunte, DM, Benhadou, F, Del Marmol, V, Guillem, P, El-Domyati, M, Abdel-Wahab, H, Antoniou, C, Dessinioti, C, Gürer, MA, Beksaç, B, Szepietowski, JC, Matusiak, L, Emtestam, L, Lapins, J, Riad, H, Doss, N, Massa, AF, Hamzavi, I, Nicholson, C, Dolenc-Voljc, M, Kim, KH, Ohn, J, Zouboulis, CC, Karagiannidis, I, Mokos, ZB, Durinec, P & Jemec, GBE 2018, 'Low and high body mass index in hidradenitis suppurativa patients-different subtypes?', Journal of the European Academy of Dermatology and Venereology : JEADV, bind 32, nr. 2, s. 307-312. https://doi.org/10.1111/jdv.14599

APA

Theut Riis, P., Saunte, D. M., Benhadou, F., Del Marmol, V., Guillem, P., El-Domyati, M., Abdel-Wahab, H., Antoniou, C., Dessinioti, C., Gürer, M. A., Beksaç, B., Szepietowski, J. C., Matusiak, L., Emtestam, L., Lapins, J., Riad, H., Doss, N., Massa, A. F., Hamzavi, I., ... Jemec, G. B. E. (2018). Low and high body mass index in hidradenitis suppurativa patients-different subtypes? Journal of the European Academy of Dermatology and Venereology : JEADV, 32(2), 307-312. https://doi.org/10.1111/jdv.14599

Vancouver

Theut Riis P, Saunte DM, Benhadou F, Del Marmol V, Guillem P, El-Domyati M o.a. Low and high body mass index in hidradenitis suppurativa patients-different subtypes? Journal of the European Academy of Dermatology and Venereology : JEADV. 2018 feb.;32(2):307-312. https://doi.org/10.1111/jdv.14599

Author

Theut Riis, P ; Saunte, D M ; Benhadou, F ; Del Marmol, V ; Guillem, P ; El-Domyati, M ; Abdel-Wahab, H ; Antoniou, C ; Dessinioti, C ; Gürer, M A ; Beksaç, B ; Szepietowski, J C ; Matusiak, L ; Emtestam, L ; Lapins, J ; Riad, H ; Doss, N ; Massa, A F ; Hamzavi, I ; Nicholson, C ; Dolenc-Voljc, M ; Kim, K H ; Ohn, J ; Zouboulis, C C ; Karagiannidis, I ; Mokos, Z B ; Durinec, P ; Jemec, G B E. / Low and high body mass index in hidradenitis suppurativa patients-different subtypes?. I: Journal of the European Academy of Dermatology and Venereology : JEADV. 2018 ; Bind 32, Nr. 2. s. 307-312.

Bibtex

@article{411fb5de229344e3b0fb0bbd72e8caee,
title = "Low and high body mass index in hidradenitis suppurativa patients-different subtypes?",
abstract = "INTRODUCTION: Overweight is a well-established risk factor for hidradenitis suppurativa (HS). In this cross-sectional study, we compare HS patients with a high body mass index (BMI) with HS patients with a low BMI to investigate differences in disease characteristics.MATERIALS AND METHOD: Patients were recruited from 17 dermatological centres from four continents. A total of 246 patients with a BMI below 25 were compared to 205 patients with a BMI of above 35.RESULTS: Patients with a high BMI suffered more severe disease (Hurley, physician global assessment, number of areas affected and patient-reported severity (PRS), P < 0.001 for all). There was no difference in smoking (P = 0.783) nor in family history (P = 0.088). In both low and high BMI patients, early onset of HS was a predictor of positive family history (P < 0.001, for each). For low BMI patients, an increase in BMI significantly increased PRS (P < 0.001). For patients with a high BMI, number of pack-years significantly increased PRS (P = 0.001). Cluster analysis of eruption patterns was location specific for low BMI patients but severity specific for high BMI patients.DISCUSSION: Patients with a low and high BMI could represent two clinically different subtypes. We suggest a non-linear relationship between BMI and impact of HS. As patients go from a low BMI patient to a high BMI patient (or from high to low), eruption patterns and risk factors may change.",
keywords = "Adult, Age of Onset, Body Mass Index, Cross-Sectional Studies, Female, Hidradenitis Suppurativa/classification, Humans, Male, Obesity/complications, Protective Factors, Risk Factors, Severity of Illness Index, Smoking, Young Adult",
author = "{Theut Riis}, P and Saunte, {D M} and F Benhadou and {Del Marmol}, V and P Guillem and M El-Domyati and H Abdel-Wahab and C Antoniou and C Dessinioti and G{\"u}rer, {M A} and B Beksa{\c c} and Szepietowski, {J C} and L Matusiak and L Emtestam and J Lapins and H Riad and N Doss and Massa, {A F} and I Hamzavi and C Nicholson and M Dolenc-Voljc and Kim, {K H} and J Ohn and Zouboulis, {C C} and I Karagiannidis and Mokos, {Z B} and P Durinec and Jemec, {G B E}",
note = "{\textcopyright} 2017 European Academy of Dermatology and Venereology.",
year = "2018",
month = feb,
doi = "10.1111/jdv.14599",
language = "English",
volume = "32",
pages = "307--312",
journal = "Journal of the European Academy of Dermatology and Venereology",
issn = "0926-9959",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Low and high body mass index in hidradenitis suppurativa patients-different subtypes?

AU - Theut Riis, P

AU - Saunte, D M

AU - Benhadou, F

AU - Del Marmol, V

AU - Guillem, P

AU - El-Domyati, M

AU - Abdel-Wahab, H

AU - Antoniou, C

AU - Dessinioti, C

AU - Gürer, M A

AU - Beksaç, B

AU - Szepietowski, J C

AU - Matusiak, L

AU - Emtestam, L

AU - Lapins, J

AU - Riad, H

AU - Doss, N

AU - Massa, A F

AU - Hamzavi, I

AU - Nicholson, C

AU - Dolenc-Voljc, M

AU - Kim, K H

AU - Ohn, J

AU - Zouboulis, C C

AU - Karagiannidis, I

AU - Mokos, Z B

AU - Durinec, P

AU - Jemec, G B E

N1 - © 2017 European Academy of Dermatology and Venereology.

PY - 2018/2

Y1 - 2018/2

N2 - INTRODUCTION: Overweight is a well-established risk factor for hidradenitis suppurativa (HS). In this cross-sectional study, we compare HS patients with a high body mass index (BMI) with HS patients with a low BMI to investigate differences in disease characteristics.MATERIALS AND METHOD: Patients were recruited from 17 dermatological centres from four continents. A total of 246 patients with a BMI below 25 were compared to 205 patients with a BMI of above 35.RESULTS: Patients with a high BMI suffered more severe disease (Hurley, physician global assessment, number of areas affected and patient-reported severity (PRS), P < 0.001 for all). There was no difference in smoking (P = 0.783) nor in family history (P = 0.088). In both low and high BMI patients, early onset of HS was a predictor of positive family history (P < 0.001, for each). For low BMI patients, an increase in BMI significantly increased PRS (P < 0.001). For patients with a high BMI, number of pack-years significantly increased PRS (P = 0.001). Cluster analysis of eruption patterns was location specific for low BMI patients but severity specific for high BMI patients.DISCUSSION: Patients with a low and high BMI could represent two clinically different subtypes. We suggest a non-linear relationship between BMI and impact of HS. As patients go from a low BMI patient to a high BMI patient (or from high to low), eruption patterns and risk factors may change.

AB - INTRODUCTION: Overweight is a well-established risk factor for hidradenitis suppurativa (HS). In this cross-sectional study, we compare HS patients with a high body mass index (BMI) with HS patients with a low BMI to investigate differences in disease characteristics.MATERIALS AND METHOD: Patients were recruited from 17 dermatological centres from four continents. A total of 246 patients with a BMI below 25 were compared to 205 patients with a BMI of above 35.RESULTS: Patients with a high BMI suffered more severe disease (Hurley, physician global assessment, number of areas affected and patient-reported severity (PRS), P < 0.001 for all). There was no difference in smoking (P = 0.783) nor in family history (P = 0.088). In both low and high BMI patients, early onset of HS was a predictor of positive family history (P < 0.001, for each). For low BMI patients, an increase in BMI significantly increased PRS (P < 0.001). For patients with a high BMI, number of pack-years significantly increased PRS (P = 0.001). Cluster analysis of eruption patterns was location specific for low BMI patients but severity specific for high BMI patients.DISCUSSION: Patients with a low and high BMI could represent two clinically different subtypes. We suggest a non-linear relationship between BMI and impact of HS. As patients go from a low BMI patient to a high BMI patient (or from high to low), eruption patterns and risk factors may change.

KW - Adult

KW - Age of Onset

KW - Body Mass Index

KW - Cross-Sectional Studies

KW - Female

KW - Hidradenitis Suppurativa/classification

KW - Humans

KW - Male

KW - Obesity/complications

KW - Protective Factors

KW - Risk Factors

KW - Severity of Illness Index

KW - Smoking

KW - Young Adult

U2 - 10.1111/jdv.14599

DO - 10.1111/jdv.14599

M3 - Journal article

C2 - 28940801

VL - 32

SP - 307

EP - 312

JO - Journal of the European Academy of Dermatology and Venereology

JF - Journal of the European Academy of Dermatology and Venereology

SN - 0926-9959

IS - 2

ER -

ID: 213885881