Long-term impact of preeclampsia on maternal endometrial cancer risk

Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt

Standard

Long-term impact of preeclampsia on maternal endometrial cancer risk. / Hallum, Sara; Pinborg, Anja; Kamper-Jørgensen, Mads.

I: B J C, Bind 114, Nr. 7, 2016, s. 809-812.

Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt

Harvard

Hallum, S, Pinborg, A & Kamper-Jørgensen, M 2016, 'Long-term impact of preeclampsia on maternal endometrial cancer risk', B J C, bind 114, nr. 7, s. 809-812. https://doi.org/10.1038/bjc.2016.55

APA

Hallum, S., Pinborg, A., & Kamper-Jørgensen, M. (2016). Long-term impact of preeclampsia on maternal endometrial cancer risk. B J C, 114(7), 809-812. https://doi.org/10.1038/bjc.2016.55

Vancouver

Hallum S, Pinborg A, Kamper-Jørgensen M. Long-term impact of preeclampsia on maternal endometrial cancer risk. B J C. 2016;114(7):809-812. https://doi.org/10.1038/bjc.2016.55

Author

Hallum, Sara ; Pinborg, Anja ; Kamper-Jørgensen, Mads. / Long-term impact of preeclampsia on maternal endometrial cancer risk. I: B J C. 2016 ; Bind 114, Nr. 7. s. 809-812.

Bibtex

@article{760ccc6e6f064160a842b8590dc65367,

title = "Long-term impact of preeclampsia on maternal endometrial cancer risk",

abstract = "BACKGROUND: Endometrial cancer is mainly dependent on oestrogen exposure. Preeclampsia has shown to reduce oestrogen levels hence preeclampsia may affect later endometrial cancer risk.METHODS: We conducted a case-control study of 523 Danish women with endometrial cancer and 52 299controls during 1978-2010. The association between preeclampsia and later endometrial cancer was evaluated overall and according to preeclampsia onset and type of endometrial cancer in conditional logistic regression models.RESULTS: We observed no overall association between preeclampsia and endometrial cancer risk (OR=1.11 (95% CI 0.68-1.81)). This was true for all endometrial cancer subtypes. In an analysis of preeclampsia onset, however, we report a markedly increased risk of endometrial cancer following early-onset preeclampsia (OR=2.64 (95% CI 1.29-5.38)).CONCLUSIONS: Although we report no obvious association between preeclampsia and endometrial cancer, studying the subset of early-onset preeclampsia may prove fruitful in further understanding the aetiology of endometrial cancer.",

keywords = "Adolescent, Adult, Case-Control Studies, Denmark, Endometrial Neoplasms, Female, Follow-Up Studies, Humans, Incidence, Middle Aged, Pre-Eclampsia, Pregnancy, Prognosis, Risk Factors, Young Adult, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't",

author = "Sara Hallum and Anja Pinborg and Mads Kamper-J{\o}rgensen",

year = "2016",

doi = "10.1038/bjc.2016.55",

language = "English",

volume = "114",

pages = "809--812",

journal = "The British journal of cancer. Supplement",

issn = "0007-0920",

publisher = "nature publishing group",

number = "7",

}

RIS

TY - JOUR

T1 - Long-term impact of preeclampsia on maternal endometrial cancer risk

AU - Hallum, Sara

AU - Pinborg, Anja

AU - Kamper-Jørgensen, Mads

PY - 2016

Y1 - 2016

N2 - BACKGROUND: Endometrial cancer is mainly dependent on oestrogen exposure. Preeclampsia has shown to reduce oestrogen levels hence preeclampsia may affect later endometrial cancer risk.METHODS: We conducted a case-control study of 523 Danish women with endometrial cancer and 52 299controls during 1978-2010. The association between preeclampsia and later endometrial cancer was evaluated overall and according to preeclampsia onset and type of endometrial cancer in conditional logistic regression models.RESULTS: We observed no overall association between preeclampsia and endometrial cancer risk (OR=1.11 (95% CI 0.68-1.81)). This was true for all endometrial cancer subtypes. In an analysis of preeclampsia onset, however, we report a markedly increased risk of endometrial cancer following early-onset preeclampsia (OR=2.64 (95% CI 1.29-5.38)).CONCLUSIONS: Although we report no obvious association between preeclampsia and endometrial cancer, studying the subset of early-onset preeclampsia may prove fruitful in further understanding the aetiology of endometrial cancer.

AB - BACKGROUND: Endometrial cancer is mainly dependent on oestrogen exposure. Preeclampsia has shown to reduce oestrogen levels hence preeclampsia may affect later endometrial cancer risk.METHODS: We conducted a case-control study of 523 Danish women with endometrial cancer and 52 299controls during 1978-2010. The association between preeclampsia and later endometrial cancer was evaluated overall and according to preeclampsia onset and type of endometrial cancer in conditional logistic regression models.RESULTS: We observed no overall association between preeclampsia and endometrial cancer risk (OR=1.11 (95% CI 0.68-1.81)). This was true for all endometrial cancer subtypes. In an analysis of preeclampsia onset, however, we report a markedly increased risk of endometrial cancer following early-onset preeclampsia (OR=2.64 (95% CI 1.29-5.38)).CONCLUSIONS: Although we report no obvious association between preeclampsia and endometrial cancer, studying the subset of early-onset preeclampsia may prove fruitful in further understanding the aetiology of endometrial cancer.

KW - Adolescent

KW - Adult

KW - Case-Control Studies

KW - Denmark

KW - Endometrial Neoplasms

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Incidence

KW - Middle Aged

KW - Pre-Eclampsia

KW - Pregnancy

KW - Prognosis

KW - Risk Factors

KW - Young Adult

KW - Comparative Study

KW - Journal Article

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

U2 - 10.1038/bjc.2016.55

DO - 10.1038/bjc.2016.55

M3 - Letter

C2 - 26964032

VL - 114

SP - 809

EP - 812

JO - The British journal of cancer. Supplement

JF - The British journal of cancer. Supplement

SN - 0007-0920

IS - 7

ER -

ID: 165718869