Lipocalin 2 is protective against E. coli pneumonia
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Lipocalin 2 is a bacteriostatic protein that binds the siderophore enterobactin, an iron-chelating molecule produced by Escherichia coli (E. coli) that is required for bacterial growth. Infection of the lungs by E. coli is rare despite a frequent exposure to this commensal bacterium. Lipocalin 2 is an effector molecule of the innate immune system and could therefore play a role in hindering growth of E. coli in the lungs.
Originalsprog | Engelsk |
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Tidsskrift | Respiratory research |
Vol/bind | 11 |
Sider (fra-til) | 96 |
ISSN | 1465-9921 |
DOI | |
Status | Udgivet - 2010 |
ID: 107122370