Laser speckle imaging of intra organ drug distribution

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Laminar flow in arteries causes streaming and uneven distribution of infused agents within the organ. This may lead to misinterpretation of experimental results and affect treatment outcomes. We monitor dynamical changes of superficial cortical blood flow in the rat kidney following different routes of administration of the vasoconstrictor angiotensin II. Our analysis reveals the appearance of large scale oscillations of the blood flow caused by inhomogeneous intra organ drug distribution.
TidsskriftBiomedical Optics Express
Udgave nummer12
Sider (fra-til)5055-5062
Antal sider8
StatusUdgivet - dec. 2015

ID: 153044633