Job insecurity and risk of diabetes: a meta-analysis of individual participant data
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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Job insecurity and risk of diabetes : a meta-analysis of individual participant data. / Ferrie, Jane E.; Virtanen, Marianna; Jokela, Markus; Madsen, Ida E H; Heikkila, Katriina; Alfredsson, Lars; Batty, G David; Bjorner, Jakob B.; Borritz, Marianne; Burr, Hermann; Dragano, Nico; Elovainio, Marko; Fransson, Eleonor I.; Knutsson, Anders; Koskenvuo, Markku; Koskinen, Aki; Kouvonen, Anne; Kumari, Meena; L. Nielsen, Martin; Nordin, Maria; Oksanen, Tuula; Pahkin, Krista; Pejtersen, Jan H.; Pentti, Jaana; Salo, Paula; Shipley, Martin J.; Suominen, Sakari B.; Tabak, Adam; Theorell, Toeres; Vaananen, Ari; Vahtera, Jussi; Westerholm, Peter J. M.; Westerlund, Hugo; Rugulies, Reiner; Nyberg, Solja T.; Kivimaki, Mika.
I: CMAJ : Canadian Medical Association Journal, Bind 188, Nr. 17-18, 06.12.2016, s. E447-E455.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Job insecurity and risk of diabetes
T2 - a meta-analysis of individual participant data
AU - Ferrie, Jane E.
AU - Virtanen, Marianna
AU - Jokela, Markus
AU - Madsen, Ida E H
AU - Heikkila, Katriina
AU - Alfredsson, Lars
AU - Batty, G David
AU - Bjorner, Jakob B.
AU - Borritz, Marianne
AU - Burr, Hermann
AU - Dragano, Nico
AU - Elovainio, Marko
AU - Fransson, Eleonor I.
AU - Knutsson, Anders
AU - Koskenvuo, Markku
AU - Koskinen, Aki
AU - Kouvonen, Anne
AU - Kumari, Meena
AU - L. Nielsen, Martin
AU - Nordin, Maria
AU - Oksanen, Tuula
AU - Pahkin, Krista
AU - Pejtersen, Jan H.
AU - Pentti, Jaana
AU - Salo, Paula
AU - Shipley, Martin J.
AU - Suominen, Sakari B.
AU - Tabak, Adam
AU - Theorell, Toeres
AU - Vaananen, Ari
AU - Vahtera, Jussi
AU - Westerholm, Peter J. M.
AU - Westerlund, Hugo
AU - Rugulies, Reiner
AU - Nyberg, Solja T.
AU - Kivimaki, Mika
PY - 2016/12/6
Y1 - 2016/12/6
N2 - Background: Job insecurity has been associated with certain health outcomes. We examined the role of job insecurity as a risk factor for incident diabetes.Methods: We used individual participant data from 8 cohort studies identified in 2 open-access data archives and 11 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. We calculated study-specific estimates of the association between job insecurity reported at baseline and incident diabetes over the follow-up period. We pooled the estimates in a meta-analysis to produce a summary risk estimate.Results: The 19 studies involved 140 825 participants from Australia, Europe and the United States, with a mean follow-up of 9.4 years and 3954 incident cases of diabetes. In the preliminary analysis adjusted for age and sex, high job insecurity was associated with an increased risk of incident diabetes compared with low job insecurity (adjusted odds ratio [OR] 1.19, 95% confidence interval [CI] 1.09–1.30). In the multivariable-adjusted analysis restricted to 15 studies with baseline data for all covariates (age, sex, socioeconomic status, obesity, physical activity, alcohol and smoking), the association was slightly attenuated (adjusted OR 1.12, 95% CI 1.01–1.24). Heterogeneity between the studies was low to moderate (age- and sex-adjusted model: I2 = 24%, p = 0.2; multivariable-adjusted model: I2 = 27%, p = 0.2). In the multivariable-adjusted analysis restricted to high-quality studies, in which the diabetes diagnosis was ascertained from electronic medical records or clinical examination, the association was similar to that in the main analysis (adjusted OR 1.19, 95% CI 1.04–1.35).Interpretation: Our findings suggest that self-reported job insecurity is associated with a modest increased risk of incident diabetes. Health care personnel should be aware of this association among workers reporting job insecurity.
AB - Background: Job insecurity has been associated with certain health outcomes. We examined the role of job insecurity as a risk factor for incident diabetes.Methods: We used individual participant data from 8 cohort studies identified in 2 open-access data archives and 11 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. We calculated study-specific estimates of the association between job insecurity reported at baseline and incident diabetes over the follow-up period. We pooled the estimates in a meta-analysis to produce a summary risk estimate.Results: The 19 studies involved 140 825 participants from Australia, Europe and the United States, with a mean follow-up of 9.4 years and 3954 incident cases of diabetes. In the preliminary analysis adjusted for age and sex, high job insecurity was associated with an increased risk of incident diabetes compared with low job insecurity (adjusted odds ratio [OR] 1.19, 95% confidence interval [CI] 1.09–1.30). In the multivariable-adjusted analysis restricted to 15 studies with baseline data for all covariates (age, sex, socioeconomic status, obesity, physical activity, alcohol and smoking), the association was slightly attenuated (adjusted OR 1.12, 95% CI 1.01–1.24). Heterogeneity between the studies was low to moderate (age- and sex-adjusted model: I2 = 24%, p = 0.2; multivariable-adjusted model: I2 = 27%, p = 0.2). In the multivariable-adjusted analysis restricted to high-quality studies, in which the diabetes diagnosis was ascertained from electronic medical records or clinical examination, the association was similar to that in the main analysis (adjusted OR 1.19, 95% CI 1.04–1.35).Interpretation: Our findings suggest that self-reported job insecurity is associated with a modest increased risk of incident diabetes. Health care personnel should be aware of this association among workers reporting job insecurity.
U2 - 10.1503/cmaj.150942
DO - 10.1503/cmaj.150942
M3 - Journal article
C2 - 27698195
VL - 188
SP - E447-E455
JO - C M A J
JF - C M A J
SN - 0008-4409
IS - 17-18
ER -
ID: 172390543