Is the SPINK1 variant p.N34S overrepresented in patients with acute pancreatitis?
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Serine Protease Inhibitor Kazal type 1 (SPINK1) protects against premature intracellular activation of trypsinogen and development of acute pancreatitis. Our aim was to determine the prevalence of SPINK1 mutations (a) in unselected patients with first-time acute pancreatitis and (b) in the Danish background population (c) in a meta-analysis to combine the results with findings in similar investigations worldwide and (d) to evaluate whether patients with SPINK1 mutations had a more severe clinical course.
Originalsprog | Engelsk |
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Tidsskrift | European Journal of Gastroenterology and Hepatology |
Vol/bind | 24 |
Udgave nummer | 3 |
Sider (fra-til) | 309-15 |
Antal sider | 7 |
ISSN | 0954-691X |
DOI | |
Status | Udgivet - 2012 |
ID: 48450115