Is the behavioural effect of diazepam in rats unique to negative secondary stimuli?

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Is the behavioural effect of diazepam in rats unique to negative secondary stimuli? / Enquist, M.; Forkman, B.; Ljungberg, T.

I: Journal of Neural Transmission, Bind 81, Nr. 2, 06.1990, s. 147-152.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Enquist, M, Forkman, B & Ljungberg, T 1990, 'Is the behavioural effect of diazepam in rats unique to negative secondary stimuli?', Journal of Neural Transmission, bind 81, nr. 2, s. 147-152. https://doi.org/10.1007/BF01245834

APA

Enquist, M., Forkman, B., & Ljungberg, T. (1990). Is the behavioural effect of diazepam in rats unique to negative secondary stimuli? Journal of Neural Transmission, 81(2), 147-152. https://doi.org/10.1007/BF01245834

Vancouver

Enquist M, Forkman B, Ljungberg T. Is the behavioural effect of diazepam in rats unique to negative secondary stimuli? Journal of Neural Transmission. 1990 jun.;81(2):147-152. https://doi.org/10.1007/BF01245834

Author

Enquist, M. ; Forkman, B. ; Ljungberg, T. / Is the behavioural effect of diazepam in rats unique to negative secondary stimuli?. I: Journal of Neural Transmission. 1990 ; Bind 81, Nr. 2. s. 147-152.

Bibtex

@article{313a4852bc344a0c964ea571ec55e154,
title = "Is the behavioural effect of diazepam in rats unique to negative secondary stimuli?",
abstract = "Studies of the behavioural effects of benzodiazepines have focused in particular on situations with negative secondary stimuli, i.e., stimuli signalling negative primary events such as punishment or non-reward. The general result is that benzodiazepines attenuate behavioural reactions to this type of stimuli. The aim of the present study was to investigate if there are any differences between positive and negative secondary stimuli in this respect. Rats were treated with diazepam in a modified Skinner box with two levers. One of the levers always gave a small reward. A lamp being ON or OFF was used as a secondary stimulus indicating if the other lever would give a large or no reward. Pretreatment with diazepam (1.0 mg/kg) did not act differently on the response to the positive or negative secondary stimulus. The main effect was a general attenuation of optimal responding with a concomitant decrease in water intake. An alternative hypothesis stating that benzodiazepines alter the reactivity to secondary stimuli more in general is supported.",
keywords = "Benzodiazepines, decision making, diazepam, operant behaviour, secondary stimulus",
author = "M. Enquist and B. Forkman and T. Ljungberg",
year = "1990",
month = jun,
doi = "10.1007/BF01245834",
language = "English",
volume = "81",
pages = "147--152",
journal = "Acta Neurovegetativa",
issn = "0375-9245",
publisher = "Springer Wien",
number = "2",

}

RIS

TY - JOUR

T1 - Is the behavioural effect of diazepam in rats unique to negative secondary stimuli?

AU - Enquist, M.

AU - Forkman, B.

AU - Ljungberg, T.

PY - 1990/6

Y1 - 1990/6

N2 - Studies of the behavioural effects of benzodiazepines have focused in particular on situations with negative secondary stimuli, i.e., stimuli signalling negative primary events such as punishment or non-reward. The general result is that benzodiazepines attenuate behavioural reactions to this type of stimuli. The aim of the present study was to investigate if there are any differences between positive and negative secondary stimuli in this respect. Rats were treated with diazepam in a modified Skinner box with two levers. One of the levers always gave a small reward. A lamp being ON or OFF was used as a secondary stimulus indicating if the other lever would give a large or no reward. Pretreatment with diazepam (1.0 mg/kg) did not act differently on the response to the positive or negative secondary stimulus. The main effect was a general attenuation of optimal responding with a concomitant decrease in water intake. An alternative hypothesis stating that benzodiazepines alter the reactivity to secondary stimuli more in general is supported.

AB - Studies of the behavioural effects of benzodiazepines have focused in particular on situations with negative secondary stimuli, i.e., stimuli signalling negative primary events such as punishment or non-reward. The general result is that benzodiazepines attenuate behavioural reactions to this type of stimuli. The aim of the present study was to investigate if there are any differences between positive and negative secondary stimuli in this respect. Rats were treated with diazepam in a modified Skinner box with two levers. One of the levers always gave a small reward. A lamp being ON or OFF was used as a secondary stimulus indicating if the other lever would give a large or no reward. Pretreatment with diazepam (1.0 mg/kg) did not act differently on the response to the positive or negative secondary stimulus. The main effect was a general attenuation of optimal responding with a concomitant decrease in water intake. An alternative hypothesis stating that benzodiazepines alter the reactivity to secondary stimuli more in general is supported.

KW - Benzodiazepines

KW - decision making

KW - diazepam

KW - operant behaviour

KW - secondary stimulus

UR - http://www.scopus.com/inward/record.url?scp=0025280444&partnerID=8YFLogxK

U2 - 10.1007/BF01245834

DO - 10.1007/BF01245834

M3 - Journal article

C2 - 2363910

AN - SCOPUS:0025280444

VL - 81

SP - 147

EP - 152

JO - Acta Neurovegetativa

JF - Acta Neurovegetativa

SN - 0375-9245

IS - 2

ER -

ID: 338346393