Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder?

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Standard

Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder? / Faurholt-Jepsen, Maria; Frost, Mads; Busk, Jonas; Christensen, Ellen Margrethe; Bardram, Jakob Eyvind; Vinberg, Maj; Kessing, Lars Vedel.

I: Bipolar Disorders, Bind 21, Nr. 7, 2019, s. 611-620.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Faurholt-Jepsen, M, Frost, M, Busk, J, Christensen, EM, Bardram, JE, Vinberg, M & Kessing, LV 2019, 'Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder?', Bipolar Disorders, bind 21, nr. 7, s. 611-620. https://doi.org/10.1111/bdi.12796

APA

Faurholt-Jepsen, M., Frost, M., Busk, J., Christensen, E. M., Bardram, J. E., Vinberg, M., & Kessing, L. V. (2019). Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder? Bipolar Disorders, 21(7), 611-620. https://doi.org/10.1111/bdi.12796

Vancouver

Faurholt-Jepsen M, Frost M, Busk J, Christensen EM, Bardram JE, Vinberg M o.a. Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder? Bipolar Disorders. 2019;21(7):611-620. https://doi.org/10.1111/bdi.12796

Author

Faurholt-Jepsen, Maria ; Frost, Mads ; Busk, Jonas ; Christensen, Ellen Margrethe ; Bardram, Jakob Eyvind ; Vinberg, Maj ; Kessing, Lars Vedel. / Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder?. I: Bipolar Disorders. 2019 ; Bind 21, Nr. 7. s. 611-620.

Bibtex

@article{88704ecd5fa64e36bd6799d81c424919,
title = "Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder?",
abstract = "OBJECTIVE: Mood instability in patients with bipolar disorder has been associated with impaired functioning and risk of relapse. The present study aimed to investigate whether increased mood instability is associated with increased perceived stress and impaired quality of life and functioning in patients with bipolar disorder.METHODS: A total of 84 patients with bipolar disorder used a smartphone-based self-monitoring system on a daily basis for 9 months. Data on perceived stress, quality of life, and clinically rated functioning were collected at five fixed time points for each patient during follow-up. A group of 37 healthy individuals served as a control comparison of perceived stress, quality of life, and psychosocial functioning.RESULTS: The majority of patients presented in full or partial remission. As hypothesized, mood instability was significantly associated with increased perceived stress (B: 10.52, 95% CI: 5.25; 15.77, P < 0.0001) and decreased quality of life (B: -12.17, 95% CI. -19.54; -4.79, P < 0.0001) and functioning (B: -12.04, 95% CI: -19.08; -4.99, P < 0.0001) in patients with bipolar disorder. There were no differences in mood instability according to prescribed psychopharmacological treatment. Compared with healthy individuals, patients reported substantially increased perceived stress and experienced decreased quality of life and decreased functioning based on researcher-blinded evaluation.CONCLUSION: Mood instability in bipolar disorder is associated with increased perceived stress and decreased quality of life and functioning even during full or partial remission. There is a need to monitor and identify subsyndromal inter-episodic symptoms. Future studies investigating the effect of treatment on mood instability are highly warranted.",
author = "Maria Faurholt-Jepsen and Mads Frost and Jonas Busk and Christensen, {Ellen Margrethe} and Bardram, {Jakob Eyvind} and Maj Vinberg and Kessing, {Lars Vedel}",
note = "{\textcopyright} 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2019",
doi = "10.1111/bdi.12796",
language = "English",
volume = "21",
pages = "611--620",
journal = "Bipolar Disorders, Supplement",
issn = "1399-2406",
publisher = "Wiley-Blackwell",
number = "7",

}

RIS

TY - JOUR

T1 - Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder?

AU - Faurholt-Jepsen, Maria

AU - Frost, Mads

AU - Busk, Jonas

AU - Christensen, Ellen Margrethe

AU - Bardram, Jakob Eyvind

AU - Vinberg, Maj

AU - Kessing, Lars Vedel

N1 - © 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2019

Y1 - 2019

N2 - OBJECTIVE: Mood instability in patients with bipolar disorder has been associated with impaired functioning and risk of relapse. The present study aimed to investigate whether increased mood instability is associated with increased perceived stress and impaired quality of life and functioning in patients with bipolar disorder.METHODS: A total of 84 patients with bipolar disorder used a smartphone-based self-monitoring system on a daily basis for 9 months. Data on perceived stress, quality of life, and clinically rated functioning were collected at five fixed time points for each patient during follow-up. A group of 37 healthy individuals served as a control comparison of perceived stress, quality of life, and psychosocial functioning.RESULTS: The majority of patients presented in full or partial remission. As hypothesized, mood instability was significantly associated with increased perceived stress (B: 10.52, 95% CI: 5.25; 15.77, P < 0.0001) and decreased quality of life (B: -12.17, 95% CI. -19.54; -4.79, P < 0.0001) and functioning (B: -12.04, 95% CI: -19.08; -4.99, P < 0.0001) in patients with bipolar disorder. There were no differences in mood instability according to prescribed psychopharmacological treatment. Compared with healthy individuals, patients reported substantially increased perceived stress and experienced decreased quality of life and decreased functioning based on researcher-blinded evaluation.CONCLUSION: Mood instability in bipolar disorder is associated with increased perceived stress and decreased quality of life and functioning even during full or partial remission. There is a need to monitor and identify subsyndromal inter-episodic symptoms. Future studies investigating the effect of treatment on mood instability are highly warranted.

AB - OBJECTIVE: Mood instability in patients with bipolar disorder has been associated with impaired functioning and risk of relapse. The present study aimed to investigate whether increased mood instability is associated with increased perceived stress and impaired quality of life and functioning in patients with bipolar disorder.METHODS: A total of 84 patients with bipolar disorder used a smartphone-based self-monitoring system on a daily basis for 9 months. Data on perceived stress, quality of life, and clinically rated functioning were collected at five fixed time points for each patient during follow-up. A group of 37 healthy individuals served as a control comparison of perceived stress, quality of life, and psychosocial functioning.RESULTS: The majority of patients presented in full or partial remission. As hypothesized, mood instability was significantly associated with increased perceived stress (B: 10.52, 95% CI: 5.25; 15.77, P < 0.0001) and decreased quality of life (B: -12.17, 95% CI. -19.54; -4.79, P < 0.0001) and functioning (B: -12.04, 95% CI: -19.08; -4.99, P < 0.0001) in patients with bipolar disorder. There were no differences in mood instability according to prescribed psychopharmacological treatment. Compared with healthy individuals, patients reported substantially increased perceived stress and experienced decreased quality of life and decreased functioning based on researcher-blinded evaluation.CONCLUSION: Mood instability in bipolar disorder is associated with increased perceived stress and decreased quality of life and functioning even during full or partial remission. There is a need to monitor and identify subsyndromal inter-episodic symptoms. Future studies investigating the effect of treatment on mood instability are highly warranted.

U2 - 10.1111/bdi.12796

DO - 10.1111/bdi.12796

M3 - Journal article

C2 - 31081991

VL - 21

SP - 611

EP - 620

JO - Bipolar Disorders, Supplement

JF - Bipolar Disorders, Supplement

SN - 1399-2406

IS - 7

ER -

ID: 236024271