Interaktion mellem warfarin og oral miconazol-gel
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Interaktion mellem warfarin og oral miconazol-gel. / Ogard, C G; Vestergaard, Henrik.
I: Ugeskrift for Laeger, Bind 162, Nr. 41, 09.10.2000, s. 5511.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Interaktion mellem warfarin og oral miconazol-gel
AU - Ogard, C G
AU - Vestergaard, Henrik
PY - 2000/10/9
Y1 - 2000/10/9
N2 - We report a case of a 76 year-old woman who had been taking warfarin for seven years because of relapsing deep venous thrombosis. Her daily maintenance dose was 5 mg. Monthly measurements of international normalised ratio (INR) were stable between 2-3. She developed oral candidiasis and miconazole gel was prescribed. One week later she developed bleeding gums. Eight days later she was admitted to the hospital with haematuria. INR was > 10. Warfarin and the miconazole gel were withdrawn. She was treated with phytonadione. INR normalised after four days and she continued warfarin treatment. Caution should be exercised whenever the combination of warfarin and miconazole gel are prescribed.
AB - We report a case of a 76 year-old woman who had been taking warfarin for seven years because of relapsing deep venous thrombosis. Her daily maintenance dose was 5 mg. Monthly measurements of international normalised ratio (INR) were stable between 2-3. She developed oral candidiasis and miconazole gel was prescribed. One week later she developed bleeding gums. Eight days later she was admitted to the hospital with haematuria. INR was > 10. Warfarin and the miconazole gel were withdrawn. She was treated with phytonadione. INR normalised after four days and she continued warfarin treatment. Caution should be exercised whenever the combination of warfarin and miconazole gel are prescribed.
KW - Aged
KW - Anticoagulants
KW - Antifungal Agents
KW - Candidiasis, Oral
KW - Drug Interactions
KW - Female
KW - Humans
KW - Miconazole
KW - Venous Thrombosis
KW - Warfarin
M3 - Tidsskriftartikel
C2 - 11068529
VL - 162
SP - 5511
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 41
ER -
ID: 92191904