Inflammation of Actinic Keratoses Induced by Combination of Carboplatin and Paclitaxel: Two Case Reports
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Inflammation of Actinic Keratoses Induced by Combination of Carboplatin and Paclitaxel : Two Case Reports. / Baglama, Špela Šuler; Trajber Horvat, Anja; Peteln, Irena; Jemec, Gregor Borut Ernst.
I: Case Reports in Dermatology, Bind 14, Nr. 3, 2022, s. 362-367.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Inflammation of Actinic Keratoses Induced by Combination of Carboplatin and Paclitaxel
T2 - Two Case Reports
AU - Baglama, Špela Šuler
AU - Trajber Horvat, Anja
AU - Peteln, Irena
AU - Jemec, Gregor Borut Ernst
N1 - Publisher Copyright: © 2022 S. Karger AG. All rights reserved.
PY - 2022
Y1 - 2022
N2 - The observations of a beneficial effect of 5-fluorouracil-induced actinic keratoses (AK) inflammation led to the development of topical fluorouracil, a product registered for the management of AK. A conscientious surveillance of AK inflammation during chemotherapy may conceivably lead to the development of further drugs for treatment of AK. A number of other chemotherapeutics have thus been linked to similar reactions without ensuing development. Here, we describe two further cases linking chemotherapy with carboplatin and paclitaxel to possible anti-AK effects, identifying them as potential treatments. Whether multidrug chemotherapy leads to stronger AK inflammation or cure AK more successfully is currently unknown.
AB - The observations of a beneficial effect of 5-fluorouracil-induced actinic keratoses (AK) inflammation led to the development of topical fluorouracil, a product registered for the management of AK. A conscientious surveillance of AK inflammation during chemotherapy may conceivably lead to the development of further drugs for treatment of AK. A number of other chemotherapeutics have thus been linked to similar reactions without ensuing development. Here, we describe two further cases linking chemotherapy with carboplatin and paclitaxel to possible anti-AK effects, identifying them as potential treatments. Whether multidrug chemotherapy leads to stronger AK inflammation or cure AK more successfully is currently unknown.
KW - Actinic keratoses
KW - Carboplatin
KW - Chemotherapy
KW - Inflammation
KW - Paclitaxel
U2 - 10.1159/000528128
DO - 10.1159/000528128
M3 - Journal article
C2 - 36655062
AN - SCOPUS:85144206258
VL - 14
SP - 362
EP - 367
JO - Case Reports in Dermatology
JF - Case Reports in Dermatology
SN - 1662-6567
IS - 3
ER -
ID: 335697607