Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells

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Standard

Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells. / Vaapil, Marica; Helczynska, Karolina; Villadsen, René; Petersen, Ole W; Johansson, Elisabet; Beckman, Siv; Larsson, Christer; Påhlman, Sven; Jögi, Annika.

I: P L o S One, Bind 7, Nr. 9, 2012, s. e46543.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Vaapil, M, Helczynska, K, Villadsen, R, Petersen, OW, Johansson, E, Beckman, S, Larsson, C, Påhlman, S & Jögi, A 2012, 'Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells', P L o S One, bind 7, nr. 9, s. e46543. https://doi.org/10.1371/journal.pone.0046543

APA

Vaapil, M., Helczynska, K., Villadsen, R., Petersen, O. W., Johansson, E., Beckman, S., Larsson, C., Påhlman, S., & Jögi, A. (2012). Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells. P L o S One, 7(9), e46543. https://doi.org/10.1371/journal.pone.0046543

Vancouver

Vaapil M, Helczynska K, Villadsen R, Petersen OW, Johansson E, Beckman S o.a. Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells. P L o S One. 2012;7(9):e46543. https://doi.org/10.1371/journal.pone.0046543

Author

Vaapil, Marica ; Helczynska, Karolina ; Villadsen, René ; Petersen, Ole W ; Johansson, Elisabet ; Beckman, Siv ; Larsson, Christer ; Påhlman, Sven ; Jögi, Annika. / Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells. I: P L o S One. 2012 ; Bind 7, Nr. 9. s. e46543.

Bibtex

@article{14abd9906d4348a18f9b208ea079defd,
title = "Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells",
abstract = "Solid tumors are less oxygenated than their tissue of origin. Low intra-tumor oxygen levels are associated with worse outcome, increased metastatic potential and immature phenotype in breast cancer. We have reported that tumor hypoxia correlates to low differentiation status in breast cancer. Less is known about effects of hypoxia on non-malignant cells. Here we address whether hypoxia influences the differentiation stage of non-malignant breast epithelial cells and potentially have bearing on early stages of tumorigenesis.",
author = "Marica Vaapil and Karolina Helczynska and Ren{\'e} Villadsen and Petersen, {Ole W} and Elisabet Johansson and Siv Beckman and Christer Larsson and Sven P{\aa}hlman and Annika J{\"o}gi",
year = "2012",
doi = "10.1371/journal.pone.0046543",
language = "English",
volume = "7",
pages = "e46543",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "9",

}

RIS

TY - JOUR

T1 - Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells

AU - Vaapil, Marica

AU - Helczynska, Karolina

AU - Villadsen, René

AU - Petersen, Ole W

AU - Johansson, Elisabet

AU - Beckman, Siv

AU - Larsson, Christer

AU - Påhlman, Sven

AU - Jögi, Annika

PY - 2012

Y1 - 2012

N2 - Solid tumors are less oxygenated than their tissue of origin. Low intra-tumor oxygen levels are associated with worse outcome, increased metastatic potential and immature phenotype in breast cancer. We have reported that tumor hypoxia correlates to low differentiation status in breast cancer. Less is known about effects of hypoxia on non-malignant cells. Here we address whether hypoxia influences the differentiation stage of non-malignant breast epithelial cells and potentially have bearing on early stages of tumorigenesis.

AB - Solid tumors are less oxygenated than their tissue of origin. Low intra-tumor oxygen levels are associated with worse outcome, increased metastatic potential and immature phenotype in breast cancer. We have reported that tumor hypoxia correlates to low differentiation status in breast cancer. Less is known about effects of hypoxia on non-malignant cells. Here we address whether hypoxia influences the differentiation stage of non-malignant breast epithelial cells and potentially have bearing on early stages of tumorigenesis.

U2 - 10.1371/journal.pone.0046543

DO - 10.1371/journal.pone.0046543

M3 - Journal article

C2 - 23029547

VL - 7

SP - e46543

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 9

ER -

ID: 42014498