Hypokalemia and rhabdomyolysis
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
The adverse drug event manager of the Capital Region of Denmark received a report of a 65-year-old male with type II diabetes and long-lasting treatment with indapamide. In addition, he had a history of a high consumption of licorice. For 2 weeks, the patient suffered from myalgia, which the general practitioner suspected to be polymyalgia rheumatica and referred him to the hospital. Initial blood samples revealed a reduced potassium concentration of 1.5 mmol/L (reference value: 6.6-4.6 mmol/L) and an elevated creatine kinase of 18,400 IU/L (reference value: 40-280 IU/L). We believe that the patient developed rhabdomyolysis due to severe hypokalemia, possibly induced by a pharmacodynamic interaction between licorice and indapamide.
Originalsprog | Engelsk |
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Tidsskrift | Journal of Pharmacology and Pharmacotherapeutics |
Vol/bind | 6 |
Udgave nummer | 2 |
Sider (fra-til) | 98-99 |
Antal sider | 2 |
ISSN | 0976-500X |
DOI | |
Status | Udgivet - 1 apr. 2015 |
ID: 389911363