Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells

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Standard

Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells. / Billestrup, Nils.

I: Biomedica Biochimica Acta, Bind 44, Nr. 1, 1985, s. 85-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Billestrup, N 1985, 'Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells', Biomedica Biochimica Acta, bind 44, nr. 1, s. 85-7.

APA

Billestrup, N. (1985). Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells. Biomedica Biochimica Acta, 44(1), 85-7.

Vancouver

Billestrup N. Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells. Biomedica Biochimica Acta. 1985;44(1):85-7.

Author

Billestrup, Nils. / Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells. I: Biomedica Biochimica Acta. 1985 ; Bind 44, Nr. 1. s. 85-7.

Bibtex

@article{e8a5187119e54382ba338c3b48af2dd5,
title = "Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells",
abstract = "Binding of 125I labelled human growth hormone to cloned insulin producing RIN-5AH cells is described. Binding was specific for somatotropic hormones since both human and rat growth hormone could compete for binding sites, whereas much higher concentrations of lactogenic hormones were needed to inhibit binding. Culture of RIN-5AH cells in the presence of hGH stimulated insulin biosynthesis by 85%.",
keywords = "Adenoma, Islet Cell, Animals, Cell Line, Growth Hormone, Insulin, Insulinoma, Rats, Receptors, Cell Surface, Receptors, Somatotropin",
author = "Nils Billestrup",
year = "1985",
language = "English",
volume = "44",
pages = "85--7",
journal = "Biomedica Biochimica Acta",
issn = "0232-766X",
publisher = "Akademie Verlag GMBH",
number = "1",

}

RIS

TY - JOUR

T1 - Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells

AU - Billestrup, Nils

PY - 1985

Y1 - 1985

N2 - Binding of 125I labelled human growth hormone to cloned insulin producing RIN-5AH cells is described. Binding was specific for somatotropic hormones since both human and rat growth hormone could compete for binding sites, whereas much higher concentrations of lactogenic hormones were needed to inhibit binding. Culture of RIN-5AH cells in the presence of hGH stimulated insulin biosynthesis by 85%.

AB - Binding of 125I labelled human growth hormone to cloned insulin producing RIN-5AH cells is described. Binding was specific for somatotropic hormones since both human and rat growth hormone could compete for binding sites, whereas much higher concentrations of lactogenic hormones were needed to inhibit binding. Culture of RIN-5AH cells in the presence of hGH stimulated insulin biosynthesis by 85%.

KW - Adenoma, Islet Cell

KW - Animals

KW - Cell Line

KW - Growth Hormone

KW - Insulin

KW - Insulinoma

KW - Rats

KW - Receptors, Cell Surface

KW - Receptors, Somatotropin

M3 - Journal article

C2 - 2986615

VL - 44

SP - 85

EP - 87

JO - Biomedica Biochimica Acta

JF - Biomedica Biochimica Acta

SN - 0232-766X

IS - 1

ER -

ID: 132900962