Genomic structure in Europeans dating back at least 36,200 years

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

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Genomic structure in Europeans dating back at least 36,200 years. / Seguin-Orlando, Andaine; Korneliussen, Thorfinn Sand; Sikora, Martin; Malaspinas, Anna Sapfo; Manica, Andrea; Moltke, Ida; Albrechtsen, Anders; Ko, Amy; Margaryan, Ashot; Moiseyev, Vyacheslav; Goebel, Ted; Westaway, Michael; Lambert, David; Khartanovich, Valeri; Wall, Jeffrey D; Nigst, Philip R; Foley, Robert A.; Lahr, Marta Mirazon; Nielsen, Rasmus; Orlando, Ludovic Antoine Alexandre; Willerslev, Eske.

I: Science, Bind 346, Nr. 6213, 2014, s. 1113-1118.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Seguin-Orlando, A, Korneliussen, TS, Sikora, M, Malaspinas, AS, Manica, A, Moltke, I, Albrechtsen, A, Ko, A, Margaryan, A, Moiseyev, V, Goebel, T, Westaway, M, Lambert, D, Khartanovich, V, Wall, JD, Nigst, PR, Foley, RA, Lahr, MM, Nielsen, R, Orlando, LAA & Willerslev, E 2014, 'Genomic structure in Europeans dating back at least 36,200 years', Science, bind 346, nr. 6213, s. 1113-1118. https://doi.org/10.1126/science.aaa0114

APA

Seguin-Orlando, A., Korneliussen, T. S., Sikora, M., Malaspinas, A. S., Manica, A., Moltke, I., Albrechtsen, A., Ko, A., Margaryan, A., Moiseyev, V., Goebel, T., Westaway, M., Lambert, D., Khartanovich, V., Wall, J. D., Nigst, P. R., Foley, R. A., Lahr, M. M., Nielsen, R., ... Willerslev, E. (2014). Genomic structure in Europeans dating back at least 36,200 years. Science, 346(6213), 1113-1118. https://doi.org/10.1126/science.aaa0114

Vancouver

Seguin-Orlando A, Korneliussen TS, Sikora M, Malaspinas AS, Manica A, Moltke I o.a. Genomic structure in Europeans dating back at least 36,200 years. Science. 2014;346(6213):1113-1118. https://doi.org/10.1126/science.aaa0114

Author

Seguin-Orlando, Andaine ; Korneliussen, Thorfinn Sand ; Sikora, Martin ; Malaspinas, Anna Sapfo ; Manica, Andrea ; Moltke, Ida ; Albrechtsen, Anders ; Ko, Amy ; Margaryan, Ashot ; Moiseyev, Vyacheslav ; Goebel, Ted ; Westaway, Michael ; Lambert, David ; Khartanovich, Valeri ; Wall, Jeffrey D ; Nigst, Philip R ; Foley, Robert A. ; Lahr, Marta Mirazon ; Nielsen, Rasmus ; Orlando, Ludovic Antoine Alexandre ; Willerslev, Eske. / Genomic structure in Europeans dating back at least 36,200 years. I: Science. 2014 ; Bind 346, Nr. 6213. s. 1113-1118.

Bibtex

@article{f29fe6dc7c284b14972e9f47f254c98b,

title = "Genomic structure in Europeans dating back at least 36,200 years",

abstract = "The origin of contemporary Europeans remains contentious. We obtained a genome sequence from Kostenki 14 in European Russia dating from 38,700 to 36,200 years ago, one of the oldest fossils of anatomically modern humans from Europe. We find that Kostenki 14 shares a close ancestry with the 24,000-year-old Mal'ta boy from central Siberia, European Mesolithic hunter-gatherers, some contemporary western Siberians, and many Europeans, but not eastern Asians. Additionally, the Kostenki 14 genome shows evidence of shared ancestry with a population basal to all Eurasians that also relates to later European Neolithic farmers. We find that Kostenki 14 contains more Neandertal DNA that is contained in longer tracts than present Europeans. Our findings reveal the timing of divergence of western Eurasians and East Asians to be more than 36,200 years ago and that European genomic structure today dates back to the Upper Paleolithic and derives from a metapopulation that at times stretched from Europe to central Asia.",

author = "Andaine Seguin-Orlando and Korneliussen, {Thorfinn Sand} and Martin Sikora and Malaspinas, {Anna Sapfo} and Andrea Manica and Ida Moltke and Anders Albrechtsen and Amy Ko and Ashot Margaryan and Vyacheslav Moiseyev and Ted Goebel and Michael Westaway and David Lambert and Valeri Khartanovich and Wall, {Jeffrey D} and Nigst, {Philip R} and Foley, {Robert A.} and Lahr, {Marta Mirazon} and Rasmus Nielsen and Orlando, {Ludovic Antoine Alexandre} and Eske Willerslev",

note = "Copyright {\textcopyright} 2014, American Association for the Advancement of Science.",

year = "2014",

doi = "10.1126/science.aaa0114",

language = "English",

volume = "346",

pages = "1113--1118",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "6213",

}

RIS

TY - JOUR

T1 - Genomic structure in Europeans dating back at least 36,200 years

AU - Seguin-Orlando, Andaine

AU - Korneliussen, Thorfinn Sand

AU - Sikora, Martin

AU - Malaspinas, Anna Sapfo

AU - Manica, Andrea

AU - Moltke, Ida

AU - Albrechtsen, Anders

AU - Ko, Amy

AU - Margaryan, Ashot

AU - Moiseyev, Vyacheslav

AU - Goebel, Ted

AU - Westaway, Michael

AU - Lambert, David

AU - Khartanovich, Valeri

AU - Wall, Jeffrey D

AU - Nigst, Philip R

AU - Foley, Robert A.

AU - Lahr, Marta Mirazon

AU - Nielsen, Rasmus

AU - Orlando, Ludovic Antoine Alexandre

AU - Willerslev, Eske

PY - 2014

Y1 - 2014

N2 - The origin of contemporary Europeans remains contentious. We obtained a genome sequence from Kostenki 14 in European Russia dating from 38,700 to 36,200 years ago, one of the oldest fossils of anatomically modern humans from Europe. We find that Kostenki 14 shares a close ancestry with the 24,000-year-old Mal'ta boy from central Siberia, European Mesolithic hunter-gatherers, some contemporary western Siberians, and many Europeans, but not eastern Asians. Additionally, the Kostenki 14 genome shows evidence of shared ancestry with a population basal to all Eurasians that also relates to later European Neolithic farmers. We find that Kostenki 14 contains more Neandertal DNA that is contained in longer tracts than present Europeans. Our findings reveal the timing of divergence of western Eurasians and East Asians to be more than 36,200 years ago and that European genomic structure today dates back to the Upper Paleolithic and derives from a metapopulation that at times stretched from Europe to central Asia.

AB - The origin of contemporary Europeans remains contentious. We obtained a genome sequence from Kostenki 14 in European Russia dating from 38,700 to 36,200 years ago, one of the oldest fossils of anatomically modern humans from Europe. We find that Kostenki 14 shares a close ancestry with the 24,000-year-old Mal'ta boy from central Siberia, European Mesolithic hunter-gatherers, some contemporary western Siberians, and many Europeans, but not eastern Asians. Additionally, the Kostenki 14 genome shows evidence of shared ancestry with a population basal to all Eurasians that also relates to later European Neolithic farmers. We find that Kostenki 14 contains more Neandertal DNA that is contained in longer tracts than present Europeans. Our findings reveal the timing of divergence of western Eurasians and East Asians to be more than 36,200 years ago and that European genomic structure today dates back to the Upper Paleolithic and derives from a metapopulation that at times stretched from Europe to central Asia.

U2 - 10.1126/science.aaa0114

DO - 10.1126/science.aaa0114

M3 - Journal article

C2 - 25378462

VL - 346

SP - 1113

EP - 1118

JO - Science

JF - Science

SN - 0036-8075

IS - 6213

ER -

ID: 128559326