Frequencies of HID-ion ampliseq ancestry panel markers among greenlanders

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Standard

Frequencies of HID-ion ampliseq ancestry panel markers among greenlanders. / Espregueira Themudo, Gonçalo; Smidt Mogensen, Helle; Børsting, Claus; Morling, Niels.

I: Forensic Science International: Genetics, Bind 24, 06.06.2016, s. 60-64.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Espregueira Themudo, G, Smidt Mogensen, H, Børsting, C & Morling, N 2016, 'Frequencies of HID-ion ampliseq ancestry panel markers among greenlanders', Forensic Science International: Genetics, bind 24, s. 60-64. https://doi.org/10.1016/j.fsigen.2016.06.001

APA

Espregueira Themudo, G., Smidt Mogensen, H., Børsting, C., & Morling, N. (2016). Frequencies of HID-ion ampliseq ancestry panel markers among greenlanders. Forensic Science International: Genetics, 24, 60-64. https://doi.org/10.1016/j.fsigen.2016.06.001

Vancouver

Espregueira Themudo G, Smidt Mogensen H, Børsting C, Morling N. Frequencies of HID-ion ampliseq ancestry panel markers among greenlanders. Forensic Science International: Genetics. 2016 jun. 6;24:60-64. https://doi.org/10.1016/j.fsigen.2016.06.001

Author

Espregueira Themudo, Gonçalo ; Smidt Mogensen, Helle ; Børsting, Claus ; Morling, Niels. / Frequencies of HID-ion ampliseq ancestry panel markers among greenlanders. I: Forensic Science International: Genetics. 2016 ; Bind 24. s. 60-64.

Bibtex

@article{034edd3126334db382ed27097c692547,

title = "Frequencies of HID-ion ampliseq ancestry panel markers among greenlanders",

abstract = "The HID-Ion AmpliSeq Ancestry Panel from Life Techologies includes 123 SNPs from the Seldin panel and 55 SNPs from Kidd panel in a single multiplex assay that helps to determine the continental biogeographic ancestry of individuals. We tested the panel on 104 Greenlanders, divided into a training set of 89 individuals and a test set of 15 individuals. All loci showed genotype distributions consistent with Hardy-Weinberg expectations. Linkage disequilibrium tests indicated that 14 pairs of loci were in association in Greenlanders. Population assignment of the training set to populations included in the HID SNP genotyper plugin placed most individuals in American, Asian, and in a few cases European populations. By including the genotype frequencies of this training set as a possible population of origin, all 15 individuals from the test set were correctly predicted to be Greenlanders using the Seldin SNPs, and nine were classified as Greenlanders using the Kidd SNPs. Population structure analysis indicated that Greenlanders have a genetic profile that is distinguishable from those of populations from America or Asia.",

author = "{Espregueira Themudo}, Gon{\c c}alo and {Smidt Mogensen}, Helle and Claus B{\o}rsting and Niels Morling",

year = "2016",

month = jun,

day = "6",

doi = "10.1016/j.fsigen.2016.06.001",

language = "English",

volume = "24",

pages = "60--64",

journal = "Forensic Science International: Genetics",

issn = "1872-4973",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Frequencies of HID-ion ampliseq ancestry panel markers among greenlanders

AU - Espregueira Themudo, Gonçalo

AU - Smidt Mogensen, Helle

AU - Børsting, Claus

AU - Morling, Niels

PY - 2016/6/6

Y1 - 2016/6/6

N2 - The HID-Ion AmpliSeq Ancestry Panel from Life Techologies includes 123 SNPs from the Seldin panel and 55 SNPs from Kidd panel in a single multiplex assay that helps to determine the continental biogeographic ancestry of individuals. We tested the panel on 104 Greenlanders, divided into a training set of 89 individuals and a test set of 15 individuals. All loci showed genotype distributions consistent with Hardy-Weinberg expectations. Linkage disequilibrium tests indicated that 14 pairs of loci were in association in Greenlanders. Population assignment of the training set to populations included in the HID SNP genotyper plugin placed most individuals in American, Asian, and in a few cases European populations. By including the genotype frequencies of this training set as a possible population of origin, all 15 individuals from the test set were correctly predicted to be Greenlanders using the Seldin SNPs, and nine were classified as Greenlanders using the Kidd SNPs. Population structure analysis indicated that Greenlanders have a genetic profile that is distinguishable from those of populations from America or Asia.

AB - The HID-Ion AmpliSeq Ancestry Panel from Life Techologies includes 123 SNPs from the Seldin panel and 55 SNPs from Kidd panel in a single multiplex assay that helps to determine the continental biogeographic ancestry of individuals. We tested the panel on 104 Greenlanders, divided into a training set of 89 individuals and a test set of 15 individuals. All loci showed genotype distributions consistent with Hardy-Weinberg expectations. Linkage disequilibrium tests indicated that 14 pairs of loci were in association in Greenlanders. Population assignment of the training set to populations included in the HID SNP genotyper plugin placed most individuals in American, Asian, and in a few cases European populations. By including the genotype frequencies of this training set as a possible population of origin, all 15 individuals from the test set were correctly predicted to be Greenlanders using the Seldin SNPs, and nine were classified as Greenlanders using the Kidd SNPs. Population structure analysis indicated that Greenlanders have a genetic profile that is distinguishable from those of populations from America or Asia.

U2 - 10.1016/j.fsigen.2016.06.001

DO - 10.1016/j.fsigen.2016.06.001

M3 - Journal article

C2 - 27326551

VL - 24

SP - 60

EP - 64

JO - Forensic Science International: Genetics

JF - Forensic Science International: Genetics

SN - 1872-4973

ER -

ID: 162990791