Fragment-based labeling using condensation reactions of six potential 5-HT7R PET tracers
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
In this work, a fragment-based labeling procedure was developed based on condensation reactions. Six F-18-labeled (arylpiperazinyl-butyl)oxindole derivatives were synthesized. These structures are interesting lead compounds with respect to development of a 5-HT7R PET tracer. They were radiolabeled in sufficient radiochemical yields, purities and molar activities for future in vivo evaluation in rodents.
Originalsprog | Engelsk |
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Tidsskrift | Journal of Radioanalytical and Nuclear Chemistry |
Vol/bind | 326 |
Sider (fra-til) | 1749-1762 |
Antal sider | 14 |
ISSN | 0236-5731 |
DOI | |
Status | Udgivet - 2020 |
ID: 252554329