This project assessed the use of multivariate auto-regressive (MAR) models to create forecasts of continuous vital signs in hospitalized patients. A total of 20 hours continuous (1/60Hz) heart rate and respiration rate from eight postoperative patients, where used to fit a centered MAR model for forecasting in windows of 15 minutes. The model was fitted using Markov Chain Monte Carlo sampling, and the model was evaluated on data from five additional patients. The results demonstrate an average RMSE in the forecast window of 11.4 (SD: 7.30) beats per minute for heart rate and 3.3 (SD:1.3) breaths per minute for respiration rate. These results indicate potential for forecasting vital signs in a clinical setting.