EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023. / Fokkens, W. J.; Viskens, An Sofie; Backer, Vibeke; Conti, Diego; de Corso, Eugenio; Gevaert, Philippe; Scadding, Glenis K.; Wagemann, Martin; Sprekelsen, Manuel Bernal; Chaker, Adam; Heffler, Enrico; Han, Joseph K.; Staeyen, Elizabeth Van; Hopkins, Claire; Mullol, Joaquim; Peters, Anju; Reitsma, Sietze; Senior, Brent A.; Hellings, Peter W.
I: Rhinology, Bind 61, Nr. 3, 2023, s. 194-202.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023
AU - Fokkens, W. J.
AU - Viskens, An Sofie
AU - Backer, Vibeke
AU - Conti, Diego
AU - de Corso, Eugenio
AU - Gevaert, Philippe
AU - Scadding, Glenis K.
AU - Wagemann, Martin
AU - Sprekelsen, Manuel Bernal
AU - Chaker, Adam
AU - Heffler, Enrico
AU - Han, Joseph K.
AU - Staeyen, Elizabeth Van
AU - Hopkins, Claire
AU - Mullol, Joaquim
AU - Peters, Anju
AU - Reitsma, Sietze
AU - Senior, Brent A.
AU - Hellings, Peter W.
N1 - Publisher Copyright: © 2023, International Rhinologic Society. All rights reserved.
PY - 2023
Y1 - 2023
N2 - Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a significant impact on the quality of life (QoL). It is typically characterized by a type 2 inflammatory reaction and by comorbidities such as asthma, allergies and NSAID-Exacerbated Respiratory Disease (N-ERD). Here, the European Forum for Research and Education in Allergy and Airway diseases discusses practical guidelines for patients on biologic treatment. Criteria for the selection of patients who would benefit from biologics were updated. Guidelines are proposed concerning the monitoring of the drug effects that provide recognition of res-ponders to the therapy and, subsequently, the decision about continuation, switching or discontinuation of a biologic. Further-more, gaps in the current knowledge and unmet needs were discussed.
AB - Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a significant impact on the quality of life (QoL). It is typically characterized by a type 2 inflammatory reaction and by comorbidities such as asthma, allergies and NSAID-Exacerbated Respiratory Disease (N-ERD). Here, the European Forum for Research and Education in Allergy and Airway diseases discusses practical guidelines for patients on biologic treatment. Criteria for the selection of patients who would benefit from biologics were updated. Guidelines are proposed concerning the monitoring of the drug effects that provide recognition of res-ponders to the therapy and, subsequently, the decision about continuation, switching or discontinuation of a biologic. Further-more, gaps in the current knowledge and unmet needs were discussed.
KW - biologics
KW - biomarkers
KW - Chronic rhinosinusitis
KW - indication
KW - nasal polyps
KW - patient selection
KW - thera-peutic response
KW - type 2 inflammation
U2 - 10.4193/Rhin22.489
DO - 10.4193/Rhin22.489
M3 - Journal article
C2 - 36999780
AN - SCOPUS:85162822635
VL - 61
SP - 194
EP - 202
JO - Rhinology. Supplement
JF - Rhinology. Supplement
SN - 1013-0047
IS - 3
ER -
ID: 366543104