Drug facilitated sexual assault with lethal outcome: GHB intoxication in a six-year-old girl

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Drug facilitated sexual assault with lethal outcome : GHB intoxication in a six-year-old girl. / Mehling, Lena-Maria; Johansen, Sys Stybe; Wang, Xin; Doberentz, Elke; Madea, Burkhard; Hess, Cornelius.

I: Forensic Science International, Bind 259, 02.2016, s. e25-e31.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Mehling, L-M, Johansen, SS, Wang, X, Doberentz, E, Madea, B & Hess, C 2016, 'Drug facilitated sexual assault with lethal outcome: GHB intoxication in a six-year-old girl', Forensic Science International, bind 259, s. e25-e31. https://doi.org/10.1016/j.forsciint.2015.12.044

APA

Mehling, L-M., Johansen, S. S., Wang, X., Doberentz, E., Madea, B., & Hess, C. (2016). Drug facilitated sexual assault with lethal outcome: GHB intoxication in a six-year-old girl. Forensic Science International, 259, e25-e31. https://doi.org/10.1016/j.forsciint.2015.12.044

Vancouver

Mehling L-M, Johansen SS, Wang X, Doberentz E, Madea B, Hess C. Drug facilitated sexual assault with lethal outcome: GHB intoxication in a six-year-old girl. Forensic Science International. 2016 feb.;259:e25-e31. https://doi.org/10.1016/j.forsciint.2015.12.044

Author

Mehling, Lena-Maria ; Johansen, Sys Stybe ; Wang, Xin ; Doberentz, Elke ; Madea, Burkhard ; Hess, Cornelius. / Drug facilitated sexual assault with lethal outcome : GHB intoxication in a six-year-old girl. I: Forensic Science International. 2016 ; Bind 259. s. e25-e31.

Bibtex

@article{287c080df7bf4c28aa6776378f73ca30,
title = "Drug facilitated sexual assault with lethal outcome: GHB intoxication in a six-year-old girl",
abstract = "A very serious case of DFSA (drug facilitated sexual assault) is presented, in which a six-year-old girl died following sedation with γ-hydroxybutyric acid (GHB). She had been sexually abused by a relative. Samples of cardiac blood, bile, vitreous humour, liver, kidney, brain tissues and hair were analysed by a LC-MS/MS method. The following GHB concentrations were determined: cardiac blood: 150 mg/l; bile: 292mg/l; vitreous humour: 58mg/l; liver: 100 mg/kg; kidney: 124.5 mg/kg, brain: 110 mg/kg. Very high GHB levels were found in the proximal part of the hair sample (about 40.9 ng/mg). In distal segments of hair - up to 12 cm distant from the hair scalp - GHB concentrations were higher than the overall found endogenous range of 2-3 ng/mg. Police investigations revealed that the uncle had also administered GHB to the older half-sister. Therefore, a sample of her hair was analysed accordingly, but unremarkable results were obtained. Comparing our toxicological results with police investigations and the offender's statements it can be assumed that the 6-year-old girl had ingested GHB. By exclusion of other causes of death a lethal intoxication with GHB could be confirmed.",
author = "Lena-Maria Mehling and Johansen, {Sys Stybe} and Xin Wang and Elke Doberentz and Burkhard Madea and Cornelius Hess",
note = "Copyright {\textcopyright} 2016 Elsevier Ireland Ltd. All rights reserved.",
year = "2016",
month = feb,
doi = "10.1016/j.forsciint.2015.12.044",
language = "English",
volume = "259",
pages = "e25--e31",
journal = "Forensic Science International",
issn = "0379-0738",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Drug facilitated sexual assault with lethal outcome

T2 - GHB intoxication in a six-year-old girl

AU - Mehling, Lena-Maria

AU - Johansen, Sys Stybe

AU - Wang, Xin

AU - Doberentz, Elke

AU - Madea, Burkhard

AU - Hess, Cornelius

N1 - Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

PY - 2016/2

Y1 - 2016/2

N2 - A very serious case of DFSA (drug facilitated sexual assault) is presented, in which a six-year-old girl died following sedation with γ-hydroxybutyric acid (GHB). She had been sexually abused by a relative. Samples of cardiac blood, bile, vitreous humour, liver, kidney, brain tissues and hair were analysed by a LC-MS/MS method. The following GHB concentrations were determined: cardiac blood: 150 mg/l; bile: 292mg/l; vitreous humour: 58mg/l; liver: 100 mg/kg; kidney: 124.5 mg/kg, brain: 110 mg/kg. Very high GHB levels were found in the proximal part of the hair sample (about 40.9 ng/mg). In distal segments of hair - up to 12 cm distant from the hair scalp - GHB concentrations were higher than the overall found endogenous range of 2-3 ng/mg. Police investigations revealed that the uncle had also administered GHB to the older half-sister. Therefore, a sample of her hair was analysed accordingly, but unremarkable results were obtained. Comparing our toxicological results with police investigations and the offender's statements it can be assumed that the 6-year-old girl had ingested GHB. By exclusion of other causes of death a lethal intoxication with GHB could be confirmed.

AB - A very serious case of DFSA (drug facilitated sexual assault) is presented, in which a six-year-old girl died following sedation with γ-hydroxybutyric acid (GHB). She had been sexually abused by a relative. Samples of cardiac blood, bile, vitreous humour, liver, kidney, brain tissues and hair were analysed by a LC-MS/MS method. The following GHB concentrations were determined: cardiac blood: 150 mg/l; bile: 292mg/l; vitreous humour: 58mg/l; liver: 100 mg/kg; kidney: 124.5 mg/kg, brain: 110 mg/kg. Very high GHB levels were found in the proximal part of the hair sample (about 40.9 ng/mg). In distal segments of hair - up to 12 cm distant from the hair scalp - GHB concentrations were higher than the overall found endogenous range of 2-3 ng/mg. Police investigations revealed that the uncle had also administered GHB to the older half-sister. Therefore, a sample of her hair was analysed accordingly, but unremarkable results were obtained. Comparing our toxicological results with police investigations and the offender's statements it can be assumed that the 6-year-old girl had ingested GHB. By exclusion of other causes of death a lethal intoxication with GHB could be confirmed.

U2 - 10.1016/j.forsciint.2015.12.044

DO - 10.1016/j.forsciint.2015.12.044

M3 - Journal article

C2 - 26774600

VL - 259

SP - e25-e31

JO - Forensic Science International

JF - Forensic Science International

SN - 0379-0738

ER -

ID: 162349975