DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma
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To explore the DNA incorporation of 6-thioguanine nucleotide levels (DNA-6TGN) during 6-mercaptopurine (6MP) therapy of childhood acute lymphoblastic leukaemia (ALL) and non-Hodgkin lymphoma (NHL) and its relation to erythrocyte levels of their metabolites: 6-thioguanine-nucleotides (E-6TGN), methylated metabolites (E-MeMP), Methotrexate polyglutamates (E-MTX), and to thiopurine methyltransferase activity (TPMT).
Originalsprog | Engelsk |
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Tidsskrift | Cancer Chemotherapy and Pharmacology |
Vol/bind | 66 |
Udgave nummer | 3 |
Sider (fra-til) | 485-91 |
Antal sider | 7 |
ISSN | 0344-5704 |
DOI | |
Status | Udgivet - 1 aug. 2010 |
ID: 33769619