Development of social functioning in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a 4-year follow-up study from age 7 to 11

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Standard

Development of social functioning in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a 4-year follow-up study from age 7 to 11. / Hemager, Nicoline; Gregersen, Maja; Christiani, Camilla Jerlang; Hjorthøj, Carsten; Knudsen, Christina Bruun; Veddum, Lotte; Andreassen, Anna Krogh; Brandt, Julie Marie; Krantz, Mette Falkenberg; Burton, Birgitte Klee; Bliksted, Vibeke; Mors, Ole; Greve, Aja Neergaard; Thorup, Anne Amalie Elgaard; Nordentoft, Merete; Jepsen, Jens Richardt Møllegaard.

I: Psychiatry Research, Bind 327, 115397, 2023.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hemager, N, Gregersen, M, Christiani, CJ, Hjorthøj, C, Knudsen, CB, Veddum, L, Andreassen, AK, Brandt, JM, Krantz, MF, Burton, BK, Bliksted, V, Mors, O, Greve, AN, Thorup, AAE, Nordentoft, M & Jepsen, JRM 2023, 'Development of social functioning in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a 4-year follow-up study from age 7 to 11', Psychiatry Research, bind 327, 115397. https://doi.org/10.1016/j.psychres.2023.115397

APA

Hemager, N., Gregersen, M., Christiani, C. J., Hjorthøj, C., Knudsen, C. B., Veddum, L., Andreassen, A. K., Brandt, J. M., Krantz, M. F., Burton, B. K., Bliksted, V., Mors, O., Greve, A. N., Thorup, A. A. E., Nordentoft, M., & Jepsen, J. R. M. (2023). Development of social functioning in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a 4-year follow-up study from age 7 to 11. Psychiatry Research, 327, [115397]. https://doi.org/10.1016/j.psychres.2023.115397

Vancouver

Hemager N, Gregersen M, Christiani CJ, Hjorthøj C, Knudsen CB, Veddum L o.a. Development of social functioning in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a 4-year follow-up study from age 7 to 11. Psychiatry Research. 2023;327. 115397. https://doi.org/10.1016/j.psychres.2023.115397

Author

Hemager, Nicoline ; Gregersen, Maja ; Christiani, Camilla Jerlang ; Hjorthøj, Carsten ; Knudsen, Christina Bruun ; Veddum, Lotte ; Andreassen, Anna Krogh ; Brandt, Julie Marie ; Krantz, Mette Falkenberg ; Burton, Birgitte Klee ; Bliksted, Vibeke ; Mors, Ole ; Greve, Aja Neergaard ; Thorup, Anne Amalie Elgaard ; Nordentoft, Merete ; Jepsen, Jens Richardt Møllegaard. / Development of social functioning in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a 4-year follow-up study from age 7 to 11. I: Psychiatry Research. 2023 ; Bind 327.

Bibtex

@article{e9cd219b3efa4e138b8a899049a5040b,

title = "Development of social functioning in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a 4-year follow-up study from age 7 to 11",

abstract = "Social functioning is a major indicator of psychosis risk and evidence is lacking regarding social functioning development during preadolescence in children at familial high risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP). We aimed to investigate development of social functioning from age 7 to 11 in children at FHR-SZ or FHR-BP compared with population-based controls. At 4-year follow-up, 179 children at FHR-SZ (mean age 12.0 y, SD 0.3), 105 children at FHR-BP (mean age 11.9 y, SD 0.2), and 181 controls (mean age 11.9 y, SD 0.2) participated. We used the Vineland-II to measure social functioning. Development of social functioning was non-significantly different across groups on the Socialization Composite score as well as the subscales Interpersonal Relations, Play and Leisure, and Coping Skills. At 4-year follow-up, children at FHR-SZ demonstrated impaired social functioning, whereas children at FHR-BP displayed social functioning comparable to controls except from impaired coping skills. From age 7 to 11, the maturational pace of social functioning in children at FHR-SZ and FHR-BP is parallel to that of controls. Children at FHR-SZ show stable social functioning deficits, whereas children at FHR-BP show normal social functioning except from emergence of discretely impaired coping skills at age 11.",

keywords = "Humans, Child, Bipolar Disorder, Follow-Up Studies, Schizophrenia, Social Interaction, Social Adjustment",

author = "Nicoline Hemager and Maja Gregersen and Christiani, {Camilla Jerlang} and Carsten Hjorth{\o}j and Knudsen, {Christina Bruun} and Lotte Veddum and Andreassen, {Anna Krogh} and Brandt, {Julie Marie} and Krantz, {Mette Falkenberg} and Burton, {Birgitte Klee} and Vibeke Bliksted and Ole Mors and Greve, {Aja Neergaard} and Thorup, {Anne Amalie Elgaard} and Merete Nordentoft and Jepsen, {Jens Richardt M{\o}llegaard}",

year = "2023",

doi = "10.1016/j.psychres.2023.115397",

language = "English",

volume = "327",

journal = "Psychiatry Research",

issn = "0165-1781",

publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Development of social functioning in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a 4-year follow-up study from age 7 to 11

AU - Hemager, Nicoline

AU - Gregersen, Maja

AU - Christiani, Camilla Jerlang

AU - Hjorthøj, Carsten

AU - Knudsen, Christina Bruun

AU - Veddum, Lotte

AU - Andreassen, Anna Krogh

AU - Brandt, Julie Marie

AU - Krantz, Mette Falkenberg

AU - Burton, Birgitte Klee

AU - Bliksted, Vibeke

AU - Mors, Ole

AU - Greve, Aja Neergaard

AU - Thorup, Anne Amalie Elgaard

AU - Nordentoft, Merete

AU - Jepsen, Jens Richardt Møllegaard

PY - 2023

Y1 - 2023

N2 - Social functioning is a major indicator of psychosis risk and evidence is lacking regarding social functioning development during preadolescence in children at familial high risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP). We aimed to investigate development of social functioning from age 7 to 11 in children at FHR-SZ or FHR-BP compared with population-based controls. At 4-year follow-up, 179 children at FHR-SZ (mean age 12.0 y, SD 0.3), 105 children at FHR-BP (mean age 11.9 y, SD 0.2), and 181 controls (mean age 11.9 y, SD 0.2) participated. We used the Vineland-II to measure social functioning. Development of social functioning was non-significantly different across groups on the Socialization Composite score as well as the subscales Interpersonal Relations, Play and Leisure, and Coping Skills. At 4-year follow-up, children at FHR-SZ demonstrated impaired social functioning, whereas children at FHR-BP displayed social functioning comparable to controls except from impaired coping skills. From age 7 to 11, the maturational pace of social functioning in children at FHR-SZ and FHR-BP is parallel to that of controls. Children at FHR-SZ show stable social functioning deficits, whereas children at FHR-BP show normal social functioning except from emergence of discretely impaired coping skills at age 11.

AB - Social functioning is a major indicator of psychosis risk and evidence is lacking regarding social functioning development during preadolescence in children at familial high risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP). We aimed to investigate development of social functioning from age 7 to 11 in children at FHR-SZ or FHR-BP compared with population-based controls. At 4-year follow-up, 179 children at FHR-SZ (mean age 12.0 y, SD 0.3), 105 children at FHR-BP (mean age 11.9 y, SD 0.2), and 181 controls (mean age 11.9 y, SD 0.2) participated. We used the Vineland-II to measure social functioning. Development of social functioning was non-significantly different across groups on the Socialization Composite score as well as the subscales Interpersonal Relations, Play and Leisure, and Coping Skills. At 4-year follow-up, children at FHR-SZ demonstrated impaired social functioning, whereas children at FHR-BP displayed social functioning comparable to controls except from impaired coping skills. From age 7 to 11, the maturational pace of social functioning in children at FHR-SZ and FHR-BP is parallel to that of controls. Children at FHR-SZ show stable social functioning deficits, whereas children at FHR-BP show normal social functioning except from emergence of discretely impaired coping skills at age 11.

KW - Humans

KW - Child

KW - Bipolar Disorder

KW - Follow-Up Studies

KW - Schizophrenia

KW - Social Interaction

KW - Social Adjustment

U2 - 10.1016/j.psychres.2023.115397

DO - 10.1016/j.psychres.2023.115397

M3 - Journal article

C2 - 37536146

VL - 327

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

M1 - 115397

ER -

ID: 387029915