Design of association studies with pooled or un-pooled next-generation sequencing data
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Most common hereditary diseases in humans are complex and multifactorial. Large-scale genome-wide association studies based on SNP genotyping have only identified a small fraction of the heritable variation of these diseases. One explanation may be that many rare variants (a minor allele frequency, MAF
Originalsprog | Engelsk |
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Tidsskrift | Genetic Epidemiology |
Vol/bind | 34 |
Udgave nummer | 5 |
Sider (fra-til) | 479-491 |
Antal sider | 13 |
ISSN | 0741-0395 |
DOI | |
Status | Udgivet - 2010 |
ID: 35312360