Critical nodes in signalling pathways: insights into insulin action
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Physiologically important cell-signalling networks are complex, and contain several points of regulation, signal divergence and crosstalk with other signalling cascades. Here, we use the concept of 'critical nodes' to define the important junctions in these pathways and illustrate their unique role using insulin signalling as a model system.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Nature Reviews. Molecular Cell Biology |
Vol/bind | 7 |
Udgave nummer | 2 |
Sider (fra-til) | 85-96 |
Antal sider | 12 |
ISSN | 1471-0072 |
DOI | |
Status | Udgivet - feb. 2006 |
- Animals, Humans, Insulin, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptor, Insulin, Signal Transduction
Forskningsområder
ID: 143328709