Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

  • Antonis C Antoniou
  • Karoline B Kuchenbaecker
  • Penny Soucy
  • Jonathan Beesley
  • Xiaoqing Chen
  • Lesley McGuffog
  • Andrew Roger Lee
  • Daniel Barrowdale
  • Sue Healey
  • Olga M Sinilnikova
  • Maria A Caligo
  • Niklas Loman
  • Katja Harbst
  • Annika Lindblom
  • Brita Arver
  • Richard Rosenquist
  • Per W. Karlsson
  • Kate Nathanson
  • Susan Domchek
  • Tim Rebbeck
  • Anna Jakubowska
  • Jan Lubinski
  • Katarzyna Jaworska
  • Katarzyna Durda
  • Elżbieta Złowowcka-Perłowska
  • Ana Osorio
  • Mercedes Durán
  • Raquel Andrés
  • Javier Benítez
  • Ute Hamann
  • Frans B Hogervorst
  • Theo A van Os
  • Senno Verhoef
  • Hanne E J Meijers-Heijboer
  • Juul Wijnen
  • Encarna B Gómez Garcia
  • Marjolijn J Ligtenberg
  • Mieke Kriege
  • J Margriet Collée
  • Margreet G E M Ausems
  • Jan C Oosterwijk
  • Susan Peock
  • Debra Frost
  • Steve D Ellis
  • Radka Platte
  • Elena Fineberg
  • D Gareth Evans
  • Fiona Lalloo
  • Nielsen, Finn Cilius
  • Gerdes, Anne-Marie Axø
  • CIMBA, SWE-BRCA
Several common alleles have been shown to be associated with breast and/or ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Recent genome-wide association studies of breast cancer have identified eight additional breast cancer susceptibility loci: rs1011970 (9p21, CDKN2A/B), rs10995190 (ZNF365), rs704010 (ZMIZ1), rs2380205 (10p15), rs614367 (11q13), rs1292011 (12q24), rs10771399 (12p11 near PTHLH) and rs865686 (9q31.2).
OriginalsprogEngelsk
TidsskriftBreast Cancer Research (Online Edition)
Vol/bind14
Udgave nummer1
Sider (fra-til)R33
ISSN1465-5411
DOI
StatusUdgivet - 2012

ID: 48450840