Combinatorial chemistry of piperidine based carbohydrate mimics
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Combinatorial chemistry of piperidine based carbohydrate mimics. / Byrgesen, Elisabeth; Nielsen, John; Willert, Marianne; Bols, Mikael.
I: Tetrahedron Letters, Bind 38, Nr. 32, 01.08.1997, s. 5697-5700.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Combinatorial chemistry of piperidine based carbohydrate mimics
AU - Byrgesen, Elisabeth
AU - Nielsen, John
AU - Willert, Marianne
AU - Bols, Mikael
PY - 1997/8/1
Y1 - 1997/8/1
N2 - Piperidine carboxylic acids and 4-hydroxypiperidine-3-carboxylic acid, the latter obtained from bakers yeast reduction of the corresponding piperidone, were coupled in solid-phase synthesis to form simplified oligosaccharide analogues. A split-and-mix synthesis approach was used to create small combinatorial libraries which were characterised by LC-MS and screened as inhibitors of glycosidases.
AB - Piperidine carboxylic acids and 4-hydroxypiperidine-3-carboxylic acid, the latter obtained from bakers yeast reduction of the corresponding piperidone, were coupled in solid-phase synthesis to form simplified oligosaccharide analogues. A split-and-mix synthesis approach was used to create small combinatorial libraries which were characterised by LC-MS and screened as inhibitors of glycosidases.
U2 - 10.1016/S0040-4039(97)01249-5
DO - 10.1016/S0040-4039(97)01249-5
M3 - Journal article
AN - SCOPUS:0030817956
VL - 38
SP - 5697
EP - 5700
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 32
ER -
ID: 131114868