Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains

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Standard

Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras : influence of amino acid composition and chain length on the activity against different bacterial strains. / Hein-Kristensen, Line; Knapp, Kolja Michael; Franzyk, Henrik; Gram, Lone.

I: B M C Microbiology, Bind 11, Nr. 1, 22.06.2011, s. 144.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hein-Kristensen, L, Knapp, KM, Franzyk, H & Gram, L 2011, 'Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains', B M C Microbiology, bind 11, nr. 1, s. 144. https://doi.org/10.1186/1471-2180-11-144

APA

Hein-Kristensen, L., Knapp, K. M., Franzyk, H., & Gram, L. (2011). Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains. B M C Microbiology, 11(1), 144. https://doi.org/10.1186/1471-2180-11-144

Vancouver

Hein-Kristensen L, Knapp KM, Franzyk H, Gram L. Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains. B M C Microbiology. 2011 jun. 22;11(1):144. https://doi.org/10.1186/1471-2180-11-144

Author

Hein-Kristensen, Line ; Knapp, Kolja Michael ; Franzyk, Henrik ; Gram, Lone. / Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras : influence of amino acid composition and chain length on the activity against different bacterial strains. I: B M C Microbiology. 2011 ; Bind 11, Nr. 1. s. 144.

Bibtex

@article{14c023e69b524fa0ab0e0fd26261c5d7,
title = "Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains",
abstract = "Characterization and use of antimicrobial peptides (AMPs) requires that their mode of action is determined. The interaction of membrane-active peptides with their target is often established using model membranes, however, the actual permeabilization of live bacterial cells and subsequent killing is usually not tested. In this report, six a-peptide/{\ss}-peptoid chimeras were examined for the effect of amino acid/peptoid substitutions and chain length on the membrane perturbation and subsequent killing of food-borne and clinical bacterial isolates.",
keywords = "Former Faculty of Pharmaceutical Sciences",
author = "Line Hein-Kristensen and Knapp, {Kolja Michael} and Henrik Franzyk and Lone Gram",
year = "2011",
month = jun,
day = "22",
doi = "10.1186/1471-2180-11-144",
language = "English",
volume = "11",
pages = "144",
journal = "BMC Microbiology",
issn = "1471-2180",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras

T2 - influence of amino acid composition and chain length on the activity against different bacterial strains

AU - Hein-Kristensen, Line

AU - Knapp, Kolja Michael

AU - Franzyk, Henrik

AU - Gram, Lone

PY - 2011/6/22

Y1 - 2011/6/22

N2 - Characterization and use of antimicrobial peptides (AMPs) requires that their mode of action is determined. The interaction of membrane-active peptides with their target is often established using model membranes, however, the actual permeabilization of live bacterial cells and subsequent killing is usually not tested. In this report, six a-peptide/ß-peptoid chimeras were examined for the effect of amino acid/peptoid substitutions and chain length on the membrane perturbation and subsequent killing of food-borne and clinical bacterial isolates.

AB - Characterization and use of antimicrobial peptides (AMPs) requires that their mode of action is determined. The interaction of membrane-active peptides with their target is often established using model membranes, however, the actual permeabilization of live bacterial cells and subsequent killing is usually not tested. In this report, six a-peptide/ß-peptoid chimeras were examined for the effect of amino acid/peptoid substitutions and chain length on the membrane perturbation and subsequent killing of food-borne and clinical bacterial isolates.

KW - Former Faculty of Pharmaceutical Sciences

U2 - 10.1186/1471-2180-11-144

DO - 10.1186/1471-2180-11-144

M3 - Journal article

C2 - 21693068

VL - 11

SP - 144

JO - BMC Microbiology

JF - BMC Microbiology

SN - 1471-2180

IS - 1

ER -

ID: 35102412