Asthma control and COPD symptom burden in patients using fixed-dose combination inhalers (SPRINT study)

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Nicolas Roche
  • Vicente Plaza
  • Backer, Vibeke
  • Job van der Palen
  • Isa Cerveri
  • Chelo Gonzalez
  • Guilherme Safioti
  • Irma Scheepstra
  • Oliver Patino
  • Dave Singh

Previous studies have found suboptimal control of symptom burden to be widespread among patients with asthma and chronic obstructive pulmonary disease (COPD). The Phase IV SPRINT study was conducted in 10 countries in Europe to assess asthma disease control and COPD symptom burden in patients treated with a fixed-dose combination (FDC) of inhaled corticosteroids (ICS) and long-acting beta agonists (LABAs). SPRINT included 1101 patients with asthma and 560 with COPD; all were receiving treatment with an FDC of ICS/LABA, delivered via various inhalers. Data were obtained over a 3-month period, during a single routine physician’s office visit. Asthma control was defined as Asthma Control Test (ACT) score >19. COPD symptom burden was assessed by COPD Assessment Test (CAT), with a CAT score <10 defining low COPD symptom burden. Among patients using any ICS/LABA FDC, 62% of patients with asthma had achieved disease control (ACT score >19) and 16% of patients with COPD had low symptom burden (CAT score <10).

OriginalsprogEngelsk
Artikelnummer1
Tidsskriftnpj Primary Care Respiratory Medicine
Vol/bind30
Udgave nummer1
Antal sider7
ISSN2055-1010
DOI
StatusUdgivet - 2020

Bibliografisk note

Funding Information:
The study protocol was approved by the Hospital Universitario de Canarias, Spain; Lakemedelsverket and the National Ethics Committee, Sweden; 25 local Ethics Committees in Italy; The Foundation for the Code for Pharmaceutical Advertising, Netherlands; 10 local Ethics Committees in Portugal; one National Ethics Committee in the UK; one National Ethics Committee in Ireland; and one National Ethics Committee in Croatia.

Funding Information:
Medical writing support was provided by Ian Grieve of Ashfield Healthcare Communications, part of UDG Healthcare plc, and was funded by Teva Pharmaceuticals. The authors were fully responsible for all content and editorial decisions, were involved at all stages of manuscript development, and have approved the final version. This study was sponsored by Teva Pharmaceuticals.

Publisher Copyright:
© 2020, The Author(s).

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