Association of psychobehavioral variables with HOMA-IR and BMI differs for men and women with prediabetes in the PREVIEW lifestyle intervention
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Association of psychobehavioral variables with HOMA-IR and BMI differs for men and women with prediabetes in the PREVIEW lifestyle intervention. / Adam, Tanja C; Drummen, Mathijs; Macdonald, Ian; Jalo, Elli; Vestentoft, Pia Siig; Martinez, J Alfredo; Handjiev-Darlenska, Teodora; Brand-Miller, Jennie; Poppitt, Sally; Stratton, Gareth; Fogelholm, Mikael; Pietiläinen, Kirsi H; Taylor, Moira; Navas-Carretero, Santiago; Winkens, Bjorn; Handjiev, Svetoslav; Muirhead, Roslyn; Silvestre, Marta; Swindell, Nils; Huttunen-Lenz, Maija; Schlicht, Wolfgang; Lam, Tony; Sundvall, Jouko; Råman, Laura; Feskens, Edith; Larsen, Thomas Meinert; Tremblay, Angelo; Raben, Anne; Westerterp-Plantenga, Margriet.
I: Diabetes Care, Bind 44, Nr. 7, 2021, s. 1491-1498.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Association of psychobehavioral variables with HOMA-IR and BMI differs for men and women with prediabetes in the PREVIEW lifestyle intervention
AU - Adam, Tanja C
AU - Drummen, Mathijs
AU - Macdonald, Ian
AU - Jalo, Elli
AU - Vestentoft, Pia Siig
AU - Martinez, J Alfredo
AU - Handjiev-Darlenska, Teodora
AU - Brand-Miller, Jennie
AU - Poppitt, Sally
AU - Stratton, Gareth
AU - Fogelholm, Mikael
AU - Pietiläinen, Kirsi H
AU - Taylor, Moira
AU - Navas-Carretero, Santiago
AU - Winkens, Bjorn
AU - Handjiev, Svetoslav
AU - Muirhead, Roslyn
AU - Silvestre, Marta
AU - Swindell, Nils
AU - Huttunen-Lenz, Maija
AU - Schlicht, Wolfgang
AU - Lam, Tony
AU - Sundvall, Jouko
AU - Råman, Laura
AU - Feskens, Edith
AU - Larsen, Thomas Meinert
AU - Tremblay, Angelo
AU - Raben, Anne
AU - Westerterp-Plantenga, Margriet
N1 - © 2021 by the American Diabetes Association.
PY - 2021
Y1 - 2021
N2 - Objective: Stress, sleep, eating behavior, and physical activity are associated with weight change and insulin resistance (IR). The aim of this analysis was the assessment of the overall and sex-specific associations of psychobehavioral variables throughout the 3-year PREVIEW intervention using the homeostatic model assessment of IR (HOMA-IR), BMI, and length of time in the study.Research design and methods: Associations of psychobehavioral variables, including stress, mood, eating behavior, physical activity (PA), and sleep, with BMI, HOMA-IR, and time spent in the study were assessed in 2,184 participants with prediabetes and overweight/obesity (n = 706 men; n = 1,478 women) during a 3-year lifestyle intervention using linear mixed modeling and general linear modeling. The study was a randomized multicenter trial using a 2 × 2 diet-by-PA design.Results: Overall, cognitive restraint and PA increased during the intervention compared with baseline, whereas BMI, HOMA-IR, disinhibition, hunger, and sleepiness decreased (all P < 0.05). Cognitive restraint and PA were negatively, whereas disinhibition, hunger, stress, and total mood disturbance were positively, associated with both BMI and HOMA-IR. Sleep duration, low sleep quality, total mood disturbance, disinhibition, and hunger scores were positively associated with HOMA-IR for men only. Participants who dropped out at 6 months had higher stress and total mood disturbance scores at baseline and throughout their time spent in the study compared with study completers.Conclusions: Eating behavior and PA, control of stress, mood disturbance, and sleep characteristics were associated with BMI, HOMA-IR, and time spent in the study, with different effects in men and women during the PREVIEW lifestyle intervention study.
AB - Objective: Stress, sleep, eating behavior, and physical activity are associated with weight change and insulin resistance (IR). The aim of this analysis was the assessment of the overall and sex-specific associations of psychobehavioral variables throughout the 3-year PREVIEW intervention using the homeostatic model assessment of IR (HOMA-IR), BMI, and length of time in the study.Research design and methods: Associations of psychobehavioral variables, including stress, mood, eating behavior, physical activity (PA), and sleep, with BMI, HOMA-IR, and time spent in the study were assessed in 2,184 participants with prediabetes and overweight/obesity (n = 706 men; n = 1,478 women) during a 3-year lifestyle intervention using linear mixed modeling and general linear modeling. The study was a randomized multicenter trial using a 2 × 2 diet-by-PA design.Results: Overall, cognitive restraint and PA increased during the intervention compared with baseline, whereas BMI, HOMA-IR, disinhibition, hunger, and sleepiness decreased (all P < 0.05). Cognitive restraint and PA were negatively, whereas disinhibition, hunger, stress, and total mood disturbance were positively, associated with both BMI and HOMA-IR. Sleep duration, low sleep quality, total mood disturbance, disinhibition, and hunger scores were positively associated with HOMA-IR for men only. Participants who dropped out at 6 months had higher stress and total mood disturbance scores at baseline and throughout their time spent in the study compared with study completers.Conclusions: Eating behavior and PA, control of stress, mood disturbance, and sleep characteristics were associated with BMI, HOMA-IR, and time spent in the study, with different effects in men and women during the PREVIEW lifestyle intervention study.
U2 - 10.2337/dc21-0059
DO - 10.2337/dc21-0059
M3 - Journal article
C2 - 34088702
VL - 44
SP - 1491
EP - 1498
JO - Diabetes Care
JF - Diabetes Care
SN - 0149-5992
IS - 7
ER -
ID: 271757074