Appendiceal Neuroendocrine Neoplasms: an Update for 2023

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Appendiceal Neuroendocrine Neoplasms : an Update for 2023. / Holmager, Pernille; Langer, Seppo W.; Kjaer, Andreas; Ringholm, Lene; Garbyal, Rajendra Singh; Hansen, Carsten Palnæs; Andreassen, Mikkel; Knigge, Ulrich.

I: Current Oncology Reports, Bind 26, Nr. 2, 2024, s. 114-120.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Holmager, P, Langer, SW, Kjaer, A, Ringholm, L, Garbyal, RS, Hansen, CP, Andreassen, M & Knigge, U 2024, 'Appendiceal Neuroendocrine Neoplasms: an Update for 2023', Current Oncology Reports, bind 26, nr. 2, s. 114-120. https://doi.org/10.1007/s11912-023-01484-4

APA

Holmager, P., Langer, S. W., Kjaer, A., Ringholm, L., Garbyal, R. S., Hansen, C. P., Andreassen, M., & Knigge, U. (2024). Appendiceal Neuroendocrine Neoplasms: an Update for 2023. Current Oncology Reports, 26(2), 114-120. https://doi.org/10.1007/s11912-023-01484-4

Vancouver

Holmager P, Langer SW, Kjaer A, Ringholm L, Garbyal RS, Hansen CP o.a. Appendiceal Neuroendocrine Neoplasms: an Update for 2023. Current Oncology Reports. 2024;26(2):114-120. https://doi.org/10.1007/s11912-023-01484-4

Author

Holmager, Pernille ; Langer, Seppo W. ; Kjaer, Andreas ; Ringholm, Lene ; Garbyal, Rajendra Singh ; Hansen, Carsten Palnæs ; Andreassen, Mikkel ; Knigge, Ulrich. / Appendiceal Neuroendocrine Neoplasms : an Update for 2023. I: Current Oncology Reports. 2024 ; Bind 26, Nr. 2. s. 114-120.

Bibtex

@article{9f5db2c0795c409684c95d5da5fad24f,
title = "Appendiceal Neuroendocrine Neoplasms: an Update for 2023",
abstract = "Purpose of Review: To summarize the literature from the last 5 years on treatment of appendiceal neuroendocrine neoplasms (aNEN). Furthermore, to evaluate the prognostic significance of lymph node metastases, indications for adjuvant treatment, and challenges of the current follow-up regimen. Recent Findings: Simple appendectomy is sufficient in tumors < 1 cm while extended surgery is indicated in tumors > 2 cm. In a multicenter study of aNENs measuring 1–2 cm, extended surgery offered no significant prognostic advantage and is now limited to incomplete tumor resection or high-grade G2 or G3 aNEN. Follow-up remains debatable, as the use of imaging and biomarkers lacks validation. Summary: While surgical procedure is well established in aNEN tumors < 1 cm and > 2 cm, the need for extended surgery in aNEN tumors 1–2 cm is questionable. Future studies should address the prognostic impact of lymph node metastases and the optimal design and duration of follow-up.",
keywords = "Appendiceal, Follow-up, Neuroendocrine neoplasm, Treatment",
author = "Pernille Holmager and Langer, {Seppo W.} and Andreas Kjaer and Lene Ringholm and Garbyal, {Rajendra Singh} and Hansen, {Carsten Paln{\ae}s} and Mikkel Andreassen and Ulrich Knigge",
note = "Publisher Copyright: {\textcopyright} 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2024",
doi = "10.1007/s11912-023-01484-4",
language = "English",
volume = "26",
pages = "114--120",
journal = "Current Oncology Reports",
issn = "1523-3790",
publisher = "Current Science, Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Appendiceal Neuroendocrine Neoplasms

T2 - an Update for 2023

AU - Holmager, Pernille

AU - Langer, Seppo W.

AU - Kjaer, Andreas

AU - Ringholm, Lene

AU - Garbyal, Rajendra Singh

AU - Hansen, Carsten Palnæs

AU - Andreassen, Mikkel

AU - Knigge, Ulrich

N1 - Publisher Copyright: © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

PY - 2024

Y1 - 2024

N2 - Purpose of Review: To summarize the literature from the last 5 years on treatment of appendiceal neuroendocrine neoplasms (aNEN). Furthermore, to evaluate the prognostic significance of lymph node metastases, indications for adjuvant treatment, and challenges of the current follow-up regimen. Recent Findings: Simple appendectomy is sufficient in tumors < 1 cm while extended surgery is indicated in tumors > 2 cm. In a multicenter study of aNENs measuring 1–2 cm, extended surgery offered no significant prognostic advantage and is now limited to incomplete tumor resection or high-grade G2 or G3 aNEN. Follow-up remains debatable, as the use of imaging and biomarkers lacks validation. Summary: While surgical procedure is well established in aNEN tumors < 1 cm and > 2 cm, the need for extended surgery in aNEN tumors 1–2 cm is questionable. Future studies should address the prognostic impact of lymph node metastases and the optimal design and duration of follow-up.

AB - Purpose of Review: To summarize the literature from the last 5 years on treatment of appendiceal neuroendocrine neoplasms (aNEN). Furthermore, to evaluate the prognostic significance of lymph node metastases, indications for adjuvant treatment, and challenges of the current follow-up regimen. Recent Findings: Simple appendectomy is sufficient in tumors < 1 cm while extended surgery is indicated in tumors > 2 cm. In a multicenter study of aNENs measuring 1–2 cm, extended surgery offered no significant prognostic advantage and is now limited to incomplete tumor resection or high-grade G2 or G3 aNEN. Follow-up remains debatable, as the use of imaging and biomarkers lacks validation. Summary: While surgical procedure is well established in aNEN tumors < 1 cm and > 2 cm, the need for extended surgery in aNEN tumors 1–2 cm is questionable. Future studies should address the prognostic impact of lymph node metastases and the optimal design and duration of follow-up.

KW - Appendiceal

KW - Follow-up

KW - Neuroendocrine neoplasm

KW - Treatment

U2 - 10.1007/s11912-023-01484-4

DO - 10.1007/s11912-023-01484-4

M3 - Review

C2 - 38168835

AN - SCOPUS:85181192700

VL - 26

SP - 114

EP - 120

JO - Current Oncology Reports

JF - Current Oncology Reports

SN - 1523-3790

IS - 2

ER -

ID: 379658039