Ancient DNA from latrines in Northern Europe and the Middle East (500 BC–1700 AD) reveals past parasites and diet

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Ancient DNA from latrines in Northern Europe and the Middle East (500 BC–1700 AD) reveals past parasites and diet. / Søe, Martin Jensen; Nejsum, Peter; Seersholm, Frederik Valeur; Fredensborg, Brian Lund; Habraken, Ruben; Haase, Kirstine; Hald, Mette Marie; Simonsen, Rikke; Højlund, Flemming; Blanke, Louise; Merkyte, Inga; Willerslev, Eske; Kapel, Christian.

I: PLOS ONE, Bind 13, Nr. 4, e0195481, 2018.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Søe, MJ, Nejsum, P, Seersholm, FV, Fredensborg, BL, Habraken, R, Haase, K, Hald, MM, Simonsen, R, Højlund, F, Blanke, L, Merkyte, I, Willerslev, E & Kapel, C 2018, 'Ancient DNA from latrines in Northern Europe and the Middle East (500 BC–1700 AD) reveals past parasites and diet', PLOS ONE, bind 13, nr. 4, e0195481. https://doi.org/10.1371/journal.pone.0195481

APA

Søe, M. J., Nejsum, P., Seersholm, F. V., Fredensborg, B. L., Habraken, R., Haase, K., Hald, M. M., Simonsen, R., Højlund, F., Blanke, L., Merkyte, I., Willerslev, E., & Kapel, C. (2018). Ancient DNA from latrines in Northern Europe and the Middle East (500 BC–1700 AD) reveals past parasites and diet. PLOS ONE, 13(4), [e0195481]. https://doi.org/10.1371/journal.pone.0195481

Vancouver

Søe MJ, Nejsum P, Seersholm FV, Fredensborg BL, Habraken R, Haase K o.a. Ancient DNA from latrines in Northern Europe and the Middle East (500 BC–1700 AD) reveals past parasites and diet. PLOS ONE. 2018;13(4). e0195481. https://doi.org/10.1371/journal.pone.0195481

Author

Søe, Martin Jensen ; Nejsum, Peter ; Seersholm, Frederik Valeur ; Fredensborg, Brian Lund ; Habraken, Ruben ; Haase, Kirstine ; Hald, Mette Marie ; Simonsen, Rikke ; Højlund, Flemming ; Blanke, Louise ; Merkyte, Inga ; Willerslev, Eske ; Kapel, Christian. / Ancient DNA from latrines in Northern Europe and the Middle East (500 BC–1700 AD) reveals past parasites and diet. I: PLOS ONE. 2018 ; Bind 13, Nr. 4.

Bibtex

@article{d5e10b453f72423b93aae4a472d4744c,
title = "Ancient DNA from latrines in Northern Europe and the Middle East (500 BC–1700 AD) reveals past parasites and diet",
abstract = "High-resolution insight into parasitic infections and diet of past populations in Northern Europe and the Middle East (500 BC- 1700 AD) was obtained by pre-concentration of parasite eggs from ancient latrines and deposits followed by shotgun sequencing of DNA. Complementary profiling of parasite, vertebrate and plant DNA proved highly informative in the study of ancient health, human-animal interactions as well as animal and plant dietary components. Most prominent were finding of soil-borne parasites transmitted directly between humans, but also meat-borne parasites that require consumption of raw or undercooked fish and pork. The detection of parasites for which sheep, horse, dog, pig, and rodents serves as definitive hosts are clear markers of domestic and synanthropic animals living in closer proximity of the respective sites. Finally, the reconstruction of full mitochondrial parasite genomes from whipworm (Ascaris lumbricoides) and roundworm species (Trichuris trichiura and Trichuris muris) and estimates of haplotype frequencies elucidates the genetic diversity and provides insights into epidemiology and parasite biology.",
author = "S{\o}e, {Martin Jensen} and Peter Nejsum and Seersholm, {Frederik Valeur} and Fredensborg, {Brian Lund} and Ruben Habraken and Kirstine Haase and Hald, {Mette Marie} and Rikke Simonsen and Flemming H{\o}jlund and Louise Blanke and Inga Merkyte and Eske Willerslev and Christian Kapel",
year = "2018",
doi = "10.1371/journal.pone.0195481",
language = "English",
volume = "13",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "4",

}

RIS

TY - JOUR

T1 - Ancient DNA from latrines in Northern Europe and the Middle East (500 BC–1700 AD) reveals past parasites and diet

AU - Søe, Martin Jensen

AU - Nejsum, Peter

AU - Seersholm, Frederik Valeur

AU - Fredensborg, Brian Lund

AU - Habraken, Ruben

AU - Haase, Kirstine

AU - Hald, Mette Marie

AU - Simonsen, Rikke

AU - Højlund, Flemming

AU - Blanke, Louise

AU - Merkyte, Inga

AU - Willerslev, Eske

AU - Kapel, Christian

PY - 2018

Y1 - 2018

N2 - High-resolution insight into parasitic infections and diet of past populations in Northern Europe and the Middle East (500 BC- 1700 AD) was obtained by pre-concentration of parasite eggs from ancient latrines and deposits followed by shotgun sequencing of DNA. Complementary profiling of parasite, vertebrate and plant DNA proved highly informative in the study of ancient health, human-animal interactions as well as animal and plant dietary components. Most prominent were finding of soil-borne parasites transmitted directly between humans, but also meat-borne parasites that require consumption of raw or undercooked fish and pork. The detection of parasites for which sheep, horse, dog, pig, and rodents serves as definitive hosts are clear markers of domestic and synanthropic animals living in closer proximity of the respective sites. Finally, the reconstruction of full mitochondrial parasite genomes from whipworm (Ascaris lumbricoides) and roundworm species (Trichuris trichiura and Trichuris muris) and estimates of haplotype frequencies elucidates the genetic diversity and provides insights into epidemiology and parasite biology.

AB - High-resolution insight into parasitic infections and diet of past populations in Northern Europe and the Middle East (500 BC- 1700 AD) was obtained by pre-concentration of parasite eggs from ancient latrines and deposits followed by shotgun sequencing of DNA. Complementary profiling of parasite, vertebrate and plant DNA proved highly informative in the study of ancient health, human-animal interactions as well as animal and plant dietary components. Most prominent were finding of soil-borne parasites transmitted directly between humans, but also meat-borne parasites that require consumption of raw or undercooked fish and pork. The detection of parasites for which sheep, horse, dog, pig, and rodents serves as definitive hosts are clear markers of domestic and synanthropic animals living in closer proximity of the respective sites. Finally, the reconstruction of full mitochondrial parasite genomes from whipworm (Ascaris lumbricoides) and roundworm species (Trichuris trichiura and Trichuris muris) and estimates of haplotype frequencies elucidates the genetic diversity and provides insights into epidemiology and parasite biology.

U2 - 10.1371/journal.pone.0195481

DO - 10.1371/journal.pone.0195481

M3 - Journal article

C2 - 29694397

VL - 13

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 4

M1 - e0195481

ER -

ID: 195899858