Anatomical mapping of the membranous septum in tricuspid and bicuspid aortic valves by cardiac computed tomography
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Anatomical mapping of the membranous septum in tricuspid and bicuspid aortic valves by cardiac computed tomography. / Campens, Laurence; Wang, Xi; Montarello, Nicholas J.; He, Jingjing; Kofoed, Klaus Fuglsang; Chen, Mao; Sondergaard, Lars; De Backer, Ole.
I: International Journal of Cardiovascular Imaging, Bind 39, Nr. 8, 08.2023, s. 1557-1559.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Anatomical mapping of the membranous septum in tricuspid and bicuspid aortic valves by cardiac computed tomography
AU - Campens, Laurence
AU - Wang, Xi
AU - Montarello, Nicholas J.
AU - He, Jingjing
AU - Kofoed, Klaus Fuglsang
AU - Chen, Mao
AU - Sondergaard, Lars
AU - De Backer, Ole
N1 - Publisher Copyright: © 2023, The Author(s), under exclusive licence to Springer Nature B.V.
PY - 2023/8
Y1 - 2023/8
N2 - A higher incidence of conduction disturbances and permanent pacemaker implantation (PPI) has been observed after transcatheter aortic valve implantation (TAVI) in patients with bicuspid aortic valves (BAVs) as compared to those with tricuspid aortic valves (TAVs). This study aimed to provide an anatomical explanation for this observation, supported by an in-depth anatomical mapping of the membranous septum (MS) in a large cohort of BAVs and TAVs using cardiac computed tomography (CT). A total of 300 cardiac CT scans were analysed, revealing a significantly shorter sub-annular length of the MS in BAVs at all measuring points compared to TAVs (p < 0.001). In the current BAV cohort, the MS was found to be at its shortest at the RCC site, measuring less than 1 mm in depth. In addition, the MS was located more anteriorly towards the RCC in BAVs, where the transcatheter aortic valve tends to be implanted deeper, and we observed a trend towards a higher PPI rate in BAVs. Future studies should investigate whether anatomical mapping of the MS in patients undergoing TAVI could be a useful tool for decision-making and potentially mitigate the risk of conduction disturbances.
AB - A higher incidence of conduction disturbances and permanent pacemaker implantation (PPI) has been observed after transcatheter aortic valve implantation (TAVI) in patients with bicuspid aortic valves (BAVs) as compared to those with tricuspid aortic valves (TAVs). This study aimed to provide an anatomical explanation for this observation, supported by an in-depth anatomical mapping of the membranous septum (MS) in a large cohort of BAVs and TAVs using cardiac computed tomography (CT). A total of 300 cardiac CT scans were analysed, revealing a significantly shorter sub-annular length of the MS in BAVs at all measuring points compared to TAVs (p < 0.001). In the current BAV cohort, the MS was found to be at its shortest at the RCC site, measuring less than 1 mm in depth. In addition, the MS was located more anteriorly towards the RCC in BAVs, where the transcatheter aortic valve tends to be implanted deeper, and we observed a trend towards a higher PPI rate in BAVs. Future studies should investigate whether anatomical mapping of the MS in patients undergoing TAVI could be a useful tool for decision-making and potentially mitigate the risk of conduction disturbances.
KW - Aortic valve
KW - Bicuspid aortic valve
KW - Conduction disturbances
KW - Membranous septum
KW - Transcatheter aortic valve replacement
UR - http://www.scopus.com/inward/record.url?scp=85158124565&partnerID=8YFLogxK
U2 - 10.1007/s10554-023-02850-w
DO - 10.1007/s10554-023-02850-w
M3 - Journal article
C2 - 37149839
AN - SCOPUS:85158124565
VL - 39
SP - 1557
EP - 1559
JO - International Journal of Cardiovascular Imaging
JF - International Journal of Cardiovascular Imaging
SN - 1569-5794
IS - 8
ER -
ID: 367753659