Alkamides from Phyllanthus fraternus
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Alkamides from Phyllanthus fraternus. / Sittie, A A; Lemmich, E; Olsen, C E; Hviid, L; Brøgger Christensen, S.
I: Planta Medica, Bind 64, Nr. 2, 1998, s. 192-3.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Alkamides from Phyllanthus fraternus
AU - Sittie, A A
AU - Lemmich, E
AU - Olsen, C E
AU - Hviid, L
AU - Brøgger Christensen, S
N1 - Keywords: Amides; Animals; Antiprotozoal Agents; Humans; Leishmania major; Lymphocyte Activation; Lymphocytes; Plants, Medicinal; Plasmodium falciparum
PY - 1998
Y1 - 1998
N2 - Two alkamides E,E-2,4-octadienamide and E,Z-2,4-decadienamide have been isolated from Phyllanthus fraternus, a plant used in Ghanaian traditional medicine to treat malaria. The compounds possess an alpha, beta, gamma, delta-unsaturated conjugated amide, a feature believed to enhance antiplasmodial activity. By means of an in vitro assay the two alkamides have been shown to possess moderate antiplasmodial activity.
AB - Two alkamides E,E-2,4-octadienamide and E,Z-2,4-decadienamide have been isolated from Phyllanthus fraternus, a plant used in Ghanaian traditional medicine to treat malaria. The compounds possess an alpha, beta, gamma, delta-unsaturated conjugated amide, a feature believed to enhance antiplasmodial activity. By means of an in vitro assay the two alkamides have been shown to possess moderate antiplasmodial activity.
M3 - Journal article
C2 - 9525113
VL - 64
SP - 192
EP - 193
JO - Planta Medica
JF - Planta Medica
SN - 0032-0943
IS - 2
ER -
ID: 6748139