Advanced heart failure: a position statement of the Heart Failure Association of the European Society of Cardiology

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

  • Maria G Crespo-Leiro
  • Marco Metra
  • Lars H Lund
  • Davor Milicic
  • Maria Rosa Costanzo
  • Gerasimos Filippatos
  • Steven Tsui
  • Eduardo Barge-Caballero
  • Nicolaas De Jonge
  • Maria Frigerio
  • Righab Hamdan
  • Tal Hasin
  • Martin Hülsmann
  • Sanem Nalbantgil
  • Luciano Potena
  • Johann Bauersachs
  • Aggeliki Gkouziouta
  • Arjang Ruhparwar
  • Arsen D Ristic
  • Ewa Straburzynska-Migaj
  • Theresa McDonagh
  • Petar Seferovic
  • Frank Ruschitzka

This article updates the Heart Failure Association of the European Society of Cardiology (ESC) 2007 classification of advanced heart failure and describes new diagnostic and treatment options for these patients. Recognizing the patient with advanced heart failure is critical to facilitate timely referral to advanced heart failure centres. Unplanned visits for heart failure decompensation, malignant arrhythmias, co-morbidities, and the 2016 ESC guidelines criteria for the diagnosis of heart failure with preserved ejection fraction are included in this updated definition. Standard treatment is, by definition, insufficient in these patients. Inotropic therapy may be used as a bridge strategy, but it is only a palliative measure when used on its own, because of the lack of outcomes data. Major progress has occurred with short-term mechanical circulatory support devices for immediate management of cardiogenic shock and long-term mechanical circulatory support for either a bridge to transplantation or as destination therapy. Heart transplantation remains the treatment of choice for patients without contraindications. Some patients will not be candidates for advanced heart failure therapies. For these patients, who are often elderly with multiple co-morbidities, management of advanced heart failure to reduce symptoms and improve quality of life should be emphasized. Robust evidence from prospective studies is lacking for most therapies for advanced heart failure. There is an urgent need to develop evidence-based treatment algorithms to prolong life when possible and in accordance with patient preferences, increase life quality, and reduce the burden of hospitalization in this vulnerable patient population.

TidsskriftEuropean Journal of Heart Failure
Udgave nummer11
Sider (fra-til)1505-1535
Antal sider31
StatusUdgivet - 2018

Bibliografisk note

© 2018 The Authors. European Journal of Heart Failure © 2018 European Society of Cardiology.

ID: 218469158