Adult Immunohistochemical Markers Fail to Detect Intratubular Germ Cell Neoplasia in Prepubertal Boys with Cryptorchidism
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Adult Immunohistochemical Markers Fail to Detect Intratubular Germ Cell Neoplasia in Prepubertal Boys with Cryptorchidism. / Kvist, Kolja; Clasen-Linde, Erik; Cortes, Dina; Petersen, Bodil Laub; Thorup, Jørgen Mogens.
I: The Journal of Urology, 03.10.2013.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Adult Immunohistochemical Markers Fail to Detect Intratubular Germ Cell Neoplasia in Prepubertal Boys with Cryptorchidism
AU - Kvist, Kolja
AU - Clasen-Linde, Erik
AU - Cortes, Dina
AU - Petersen, Bodil Laub
AU - Thorup, Jørgen Mogens
N1 - Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
PY - 2013/10/3
Y1 - 2013/10/3
N2 - Intratubular germ cell neoplasia (ITGCN) is a precursor to testicular germ cell cancer. It is characterized by large germ cells with large nuclei with a hyperchromatic, coarse chromatin pattern, large prominent nucleoli and abundant pale cytoplasm. In prepubertal boys these cells are located both centrally and peripherally mixed with normal cells in the seminiferous tubules. The aim of study was to evaluate the impact of adult ITGCN-marking immunohistochemical methods in screening for ITGCN in boys with cryptorchidism.
AB - Intratubular germ cell neoplasia (ITGCN) is a precursor to testicular germ cell cancer. It is characterized by large germ cells with large nuclei with a hyperchromatic, coarse chromatin pattern, large prominent nucleoli and abundant pale cytoplasm. In prepubertal boys these cells are located both centrally and peripherally mixed with normal cells in the seminiferous tubules. The aim of study was to evaluate the impact of adult ITGCN-marking immunohistochemical methods in screening for ITGCN in boys with cryptorchidism.
U2 - 10.1016/j.juro.2013.10.001
DO - 10.1016/j.juro.2013.10.001
M3 - Journal article
C2 - 24095908
JO - Journal of Urology
JF - Journal of Urology
SN - 0022-5347
ER -
ID: 52941455