Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells

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Standard

Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells. / Kemp, Kåre; Akanmori, Bartholomew D; Kurtzhals, Jørgen A L; Adabayeri, Victoria; Goka, Bamenla Q; Hviid, Lars.

I: Parasite Immunology, Bind 24, Nr. 11-12, 2002, s. 545-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Kemp, K, Akanmori, BD, Kurtzhals, JAL, Adabayeri, V, Goka, BQ & Hviid, L 2002, 'Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells', Parasite Immunology, bind 24, nr. 11-12, s. 545-8.

APA

Kemp, K., Akanmori, B. D., Kurtzhals, J. A. L., Adabayeri, V., Goka, B. Q., & Hviid, L. (2002). Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells. Parasite Immunology, 24(11-12), 545-8.

Vancouver

Kemp K, Akanmori BD, Kurtzhals JAL, Adabayeri V, Goka BQ, Hviid L. Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells. Parasite Immunology. 2002;24(11-12):545-8.

Author

Kemp, Kåre ; Akanmori, Bartholomew D ; Kurtzhals, Jørgen A L ; Adabayeri, Victoria ; Goka, Bamenla Q ; Hviid, Lars. / Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells. I: Parasite Immunology. 2002 ; Bind 24, Nr. 11-12. s. 545-8.

Bibtex

@article{1529ebc0a19911dd95e9000ea68e967b,
title = "Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells",
abstract = "P. falciparum malaria is associated with increased activation among peripheral lymphocytes. In the present study, we investigated markers of susceptibility to apoptosis and expression of IFN-gamma and IL-4 by CD28-and CD28+T cells in West African children with acute P. falciparum malaria. The study showed increased susceptibility to apoptosis and cytokine production among T lymphocytes during acute malaria but also that T cells, in particular IFN-gamma producing CD28-T cells, were substantially reduced. These results are in line with previous studies suggesting that certain T cell subsets are sequestered away from the peripheral blood during P. falciparum malaria.",
author = "K{\aa}re Kemp and Akanmori, {Bartholomew D} and Kurtzhals, {J{\o}rgen A L} and Victoria Adabayeri and Goka, {Bamenla Q} and Lars Hviid",
note = "Keywords: Acute Disease; Animals; Antigens, CD28; Antigens, CD95; Apoptosis; Genes, bcl-2; Humans; Interferon Type II; Interleukin-4; Malaria, Falciparum; Plasmodium falciparum; T-Lymphocyte Subsets; T-Lymphocytes",
year = "2002",
language = "English",
volume = "24",
pages = "545--8",
journal = "Parasite Immunology",
issn = "0141-9838",
publisher = "Wiley-Blackwell",
number = "11-12",

}

RIS

TY - JOUR

T1 - Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells

AU - Kemp, Kåre

AU - Akanmori, Bartholomew D

AU - Kurtzhals, Jørgen A L

AU - Adabayeri, Victoria

AU - Goka, Bamenla Q

AU - Hviid, Lars

N1 - Keywords: Acute Disease; Animals; Antigens, CD28; Antigens, CD95; Apoptosis; Genes, bcl-2; Humans; Interferon Type II; Interleukin-4; Malaria, Falciparum; Plasmodium falciparum; T-Lymphocyte Subsets; T-Lymphocytes

PY - 2002

Y1 - 2002

N2 - P. falciparum malaria is associated with increased activation among peripheral lymphocytes. In the present study, we investigated markers of susceptibility to apoptosis and expression of IFN-gamma and IL-4 by CD28-and CD28+T cells in West African children with acute P. falciparum malaria. The study showed increased susceptibility to apoptosis and cytokine production among T lymphocytes during acute malaria but also that T cells, in particular IFN-gamma producing CD28-T cells, were substantially reduced. These results are in line with previous studies suggesting that certain T cell subsets are sequestered away from the peripheral blood during P. falciparum malaria.

AB - P. falciparum malaria is associated with increased activation among peripheral lymphocytes. In the present study, we investigated markers of susceptibility to apoptosis and expression of IFN-gamma and IL-4 by CD28-and CD28+T cells in West African children with acute P. falciparum malaria. The study showed increased susceptibility to apoptosis and cytokine production among T lymphocytes during acute malaria but also that T cells, in particular IFN-gamma producing CD28-T cells, were substantially reduced. These results are in line with previous studies suggesting that certain T cell subsets are sequestered away from the peripheral blood during P. falciparum malaria.

M3 - Journal article

C2 - 12694605

VL - 24

SP - 545

EP - 548

JO - Parasite Immunology

JF - Parasite Immunology

SN - 0141-9838

IS - 11-12

ER -

ID: 7691293