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A global catalog of whole-genome diversity from 233 primate species. / Kuderna, Lukas F.K.; Gao, Hong; Janiak, Mareike C.; Kuhlwilm, Martin; Orkin, Joseph D.; Bataillon, Thomas; Manu, Shivakumara; Valenzuela, Alejandro; Bergman, Juraj; Rousselle, Marjolaine; Silva, Felipe Ennes; Agueda, Lidia; Blanc, Julie; Gut, Marta; de Vries, Dorien; Goodhead, Ian; Harris, R. Alan; Raveendran, Muthuswamy; Jensen, Axel; Chuma, Idrissa S.; Horvath, Julie E.; Hvilsom, Christina; Juan, David; Frandsen, Peter; Schraiber, Joshua G.; de Melo, Fabiano R.; Bertuol, Fabrício; Byrne, Hazel; Sampaio, Iracilda; Farias, Izeni; Valsecchi, João; Messias, Malu; da Silva, Maria N.F.; Trivedi, Mihir; Rossi, Rogerio; Hrbek, Tomas; Andriaholinirina, Nicole; Rabarivola, Clément J.; Zaramody, Alphonse; Jolly, Clifford J.; Phillips-Conroy, Jane; Wilkerson, Gregory; Abee, Christian; Simmons, Joe H.; Fernandez-Duque, Eduardo; Kanthaswamy, Sree; Shiferaw, Fekadu; Wu, Dongdong; Zhou, Long; Shao, Yong; Zhang, Guojie; Keyyu, Julius D.; Knauf, Sascha; Le, Minh D.; Lizano, Esther; Merker, Stefan; Navarro, Arcadi; Nadler, Tilo; Khor, Chiea Chuen; Lee, Jessica; Tan, Patrick; Lim, Weng Khong; Kitchener, Andrew C.; Zinner, Dietmar; Gut, Ivo; Melin, Amanda D.; Guschanski, Katerina; Schierup, Mikkel Heide; Beck, Robin M.D.; Umapathy, Govindhaswamy; Roos, Christian; Boubli, Jean P.; Rogers, Jeffrey; Farh, Kyle Kai How; Marques Bonet, Tomas.
I:
Science (New York, N.Y.), Bind 380, Nr. 6648, 2023, s. 906-913.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Kuderna, LFK, Gao, H, Janiak, MC, Kuhlwilm, M, Orkin, JD, Bataillon, T, Manu, S, Valenzuela, A, Bergman, J, Rousselle, M, Silva, FE, Agueda, L, Blanc, J, Gut, M, de Vries, D, Goodhead, I, Harris, RA, Raveendran, M, Jensen, A, Chuma, IS, Horvath, JE, Hvilsom, C, Juan, D, Frandsen, P, Schraiber, JG, de Melo, FR, Bertuol, F, Byrne, H, Sampaio, I, Farias, I, Valsecchi, J, Messias, M, da Silva, MNF, Trivedi, M, Rossi, R, Hrbek, T, Andriaholinirina, N, Rabarivola, CJ, Zaramody, A, Jolly, CJ, Phillips-Conroy, J, Wilkerson, G, Abee, C, Simmons, JH, Fernandez-Duque, E, Kanthaswamy, S, Shiferaw, F, Wu, D, Zhou, L, Shao, Y
, Zhang, G, Keyyu, JD, Knauf, S, Le, MD, Lizano, E, Merker, S, Navarro, A, Nadler, T, Khor, CC, Lee, J, Tan, P, Lim, WK, Kitchener, AC, Zinner, D, Gut, I, Melin, AD, Guschanski, K, Schierup, MH, Beck, RMD, Umapathy, G, Roos, C, Boubli, JP, Rogers, J, Farh, KKH & Marques Bonet, T 2023, '
A global catalog of whole-genome diversity from 233 primate species',
Science (New York, N.Y.), bind 380, nr. 6648, s. 906-913.
https://doi.org/10.1126/science.abn7829APA
Kuderna, L. F. K., Gao, H., Janiak, M. C., Kuhlwilm, M., Orkin, J. D., Bataillon, T., Manu, S., Valenzuela, A., Bergman, J., Rousselle, M., Silva, F. E., Agueda, L., Blanc, J., Gut, M., de Vries, D., Goodhead, I., Harris, R. A., Raveendran, M., Jensen, A., ... Marques Bonet, T. (2023).
A global catalog of whole-genome diversity from 233 primate species.
Science (New York, N.Y.),
380(6648), 906-913.
https://doi.org/10.1126/science.abn7829Vancouver
Kuderna LFK, Gao H, Janiak MC, Kuhlwilm M, Orkin JD, Bataillon T o.a.
A global catalog of whole-genome diversity from 233 primate species.
Science (New York, N.Y.). 2023;380(6648):906-913.
https://doi.org/10.1126/science.abn7829Author
Kuderna, Lukas F.K. ; Gao, Hong ; Janiak, Mareike C. ; Kuhlwilm, Martin ; Orkin, Joseph D. ; Bataillon, Thomas ; Manu, Shivakumara ; Valenzuela, Alejandro ; Bergman, Juraj ; Rousselle, Marjolaine ; Silva, Felipe Ennes ; Agueda, Lidia ; Blanc, Julie ; Gut, Marta ; de Vries, Dorien ; Goodhead, Ian ; Harris, R. Alan ; Raveendran, Muthuswamy ; Jensen, Axel ; Chuma, Idrissa S. ; Horvath, Julie E. ; Hvilsom, Christina ; Juan, David ; Frandsen, Peter ; Schraiber, Joshua G. ; de Melo, Fabiano R. ; Bertuol, Fabrício ; Byrne, Hazel ; Sampaio, Iracilda ; Farias, Izeni ; Valsecchi, João ; Messias, Malu ; da Silva, Maria N.F. ; Trivedi, Mihir ; Rossi, Rogerio ; Hrbek, Tomas ; Andriaholinirina, Nicole ; Rabarivola, Clément J. ; Zaramody, Alphonse ; Jolly, Clifford J. ; Phillips-Conroy, Jane ; Wilkerson, Gregory ; Abee, Christian ; Simmons, Joe H. ; Fernandez-Duque, Eduardo ; Kanthaswamy, Sree ; Shiferaw, Fekadu ; Wu, Dongdong ; Zhou, Long ; Shao, Yong ; Zhang, Guojie ; Keyyu, Julius D. ; Knauf, Sascha ; Le, Minh D. ; Lizano, Esther ; Merker, Stefan ; Navarro, Arcadi ; Nadler, Tilo ; Khor, Chiea Chuen ; Lee, Jessica ; Tan, Patrick ; Lim, Weng Khong ; Kitchener, Andrew C. ; Zinner, Dietmar ; Gut, Ivo ; Melin, Amanda D. ; Guschanski, Katerina ; Schierup, Mikkel Heide ; Beck, Robin M.D. ; Umapathy, Govindhaswamy ; Roos, Christian ; Boubli, Jean P. ; Rogers, Jeffrey ; Farh, Kyle Kai How ; Marques Bonet, Tomas. / A global catalog of whole-genome diversity from 233 primate species. I: Science (New York, N.Y.). 2023 ; Bind 380, Nr. 6648. s. 906-913.
Bibtex
@article{0e5305e36b4b44a8bd1b8e5b8c1adb11,
title = "A global catalog of whole-genome diversity from 233 primate species",
abstract = "The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of that diversity provides insight into long-standing questions in evolutionary and conservation biology and is urgent given severe threats these species are facing. Here, we present high-coverage whole-genome data from 233 primate species representing 86% of genera and all 16 families. This dataset was used, together with fossil calibration, to create a nuclear DNA phylogeny and to reassess evolutionary divergence times among primate clades. We found within-species genetic diversity across families and geographic regions to be associated with climate and sociality, but not with extinction risk. Furthermore, mutation rates differ across species, potentially influenced by effective population sizes. Lastly, we identified extensive recurrence of missense mutations previously thought to be human specific. This study will open a wide range of research avenues for future primate genomic research.",
author = "Kuderna, {Lukas F.K.} and Hong Gao and Janiak, {Mareike C.} and Martin Kuhlwilm and Orkin, {Joseph D.} and Thomas Bataillon and Shivakumara Manu and Alejandro Valenzuela and Juraj Bergman and Marjolaine Rousselle and Silva, {Felipe Ennes} and Lidia Agueda and Julie Blanc and Marta Gut and {de Vries}, Dorien and Ian Goodhead and Harris, {R. Alan} and Muthuswamy Raveendran and Axel Jensen and Chuma, {Idrissa S.} and Horvath, {Julie E.} and Christina Hvilsom and David Juan and Peter Frandsen and Schraiber, {Joshua G.} and {de Melo}, {Fabiano R.} and Fabr{\'i}cio Bertuol and Hazel Byrne and Iracilda Sampaio and Izeni Farias and Jo{\~a}o Valsecchi and Malu Messias and {da Silva}, {Maria N.F.} and Mihir Trivedi and Rogerio Rossi and Tomas Hrbek and Nicole Andriaholinirina and Rabarivola, {Cl{\'e}ment J.} and Alphonse Zaramody and Jolly, {Clifford J.} and Jane Phillips-Conroy and Gregory Wilkerson and Christian Abee and Simmons, {Joe H.} and Eduardo Fernandez-Duque and Sree Kanthaswamy and Fekadu Shiferaw and Dongdong Wu and Long Zhou and Yong Shao and Guojie Zhang and Keyyu, {Julius D.} and Sascha Knauf and Le, {Minh D.} and Esther Lizano and Stefan Merker and Arcadi Navarro and Tilo Nadler and Khor, {Chiea Chuen} and Jessica Lee and Patrick Tan and Lim, {Weng Khong} and Kitchener, {Andrew C.} and Dietmar Zinner and Ivo Gut and Melin, {Amanda D.} and Katerina Guschanski and Schierup, {Mikkel Heide} and Beck, {Robin M.D.} and Govindhaswamy Umapathy and Christian Roos and Boubli, {Jean P.} and Jeffrey Rogers and Farh, {Kyle Kai How} and {Marques Bonet}, Tomas",
year = "2023",
doi = "10.1126/science.abn7829",
language = "English",
volume = "380",
pages = "906--913",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "6648",
}
RIS
TY - JOUR
T1 - A global catalog of whole-genome diversity from 233 primate species
AU - Kuderna, Lukas F.K.
AU - Gao, Hong
AU - Janiak, Mareike C.
AU - Kuhlwilm, Martin
AU - Orkin, Joseph D.
AU - Bataillon, Thomas
AU - Manu, Shivakumara
AU - Valenzuela, Alejandro
AU - Bergman, Juraj
AU - Rousselle, Marjolaine
AU - Silva, Felipe Ennes
AU - Agueda, Lidia
AU - Blanc, Julie
AU - Gut, Marta
AU - de Vries, Dorien
AU - Goodhead, Ian
AU - Harris, R. Alan
AU - Raveendran, Muthuswamy
AU - Jensen, Axel
AU - Chuma, Idrissa S.
AU - Horvath, Julie E.
AU - Hvilsom, Christina
AU - Juan, David
AU - Frandsen, Peter
AU - Schraiber, Joshua G.
AU - de Melo, Fabiano R.
AU - Bertuol, Fabrício
AU - Byrne, Hazel
AU - Sampaio, Iracilda
AU - Farias, Izeni
AU - Valsecchi, João
AU - Messias, Malu
AU - da Silva, Maria N.F.
AU - Trivedi, Mihir
AU - Rossi, Rogerio
AU - Hrbek, Tomas
AU - Andriaholinirina, Nicole
AU - Rabarivola, Clément J.
AU - Zaramody, Alphonse
AU - Jolly, Clifford J.
AU - Phillips-Conroy, Jane
AU - Wilkerson, Gregory
AU - Abee, Christian
AU - Simmons, Joe H.
AU - Fernandez-Duque, Eduardo
AU - Kanthaswamy, Sree
AU - Shiferaw, Fekadu
AU - Wu, Dongdong
AU - Zhou, Long
AU - Shao, Yong
AU - Zhang, Guojie
AU - Keyyu, Julius D.
AU - Knauf, Sascha
AU - Le, Minh D.
AU - Lizano, Esther
AU - Merker, Stefan
AU - Navarro, Arcadi
AU - Nadler, Tilo
AU - Khor, Chiea Chuen
AU - Lee, Jessica
AU - Tan, Patrick
AU - Lim, Weng Khong
AU - Kitchener, Andrew C.
AU - Zinner, Dietmar
AU - Gut, Ivo
AU - Melin, Amanda D.
AU - Guschanski, Katerina
AU - Schierup, Mikkel Heide
AU - Beck, Robin M.D.
AU - Umapathy, Govindhaswamy
AU - Roos, Christian
AU - Boubli, Jean P.
AU - Rogers, Jeffrey
AU - Farh, Kyle Kai How
AU - Marques Bonet, Tomas
PY - 2023
Y1 - 2023
N2 - The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of that diversity provides insight into long-standing questions in evolutionary and conservation biology and is urgent given severe threats these species are facing. Here, we present high-coverage whole-genome data from 233 primate species representing 86% of genera and all 16 families. This dataset was used, together with fossil calibration, to create a nuclear DNA phylogeny and to reassess evolutionary divergence times among primate clades. We found within-species genetic diversity across families and geographic regions to be associated with climate and sociality, but not with extinction risk. Furthermore, mutation rates differ across species, potentially influenced by effective population sizes. Lastly, we identified extensive recurrence of missense mutations previously thought to be human specific. This study will open a wide range of research avenues for future primate genomic research.
AB - The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of that diversity provides insight into long-standing questions in evolutionary and conservation biology and is urgent given severe threats these species are facing. Here, we present high-coverage whole-genome data from 233 primate species representing 86% of genera and all 16 families. This dataset was used, together with fossil calibration, to create a nuclear DNA phylogeny and to reassess evolutionary divergence times among primate clades. We found within-species genetic diversity across families and geographic regions to be associated with climate and sociality, but not with extinction risk. Furthermore, mutation rates differ across species, potentially influenced by effective population sizes. Lastly, we identified extensive recurrence of missense mutations previously thought to be human specific. This study will open a wide range of research avenues for future primate genomic research.
U2 - 10.1126/science.abn7829
DO - 10.1126/science.abn7829
M3 - Journal article
C2 - 37262161
AN - SCOPUS:85160593037
VL - 380
SP - 906
EP - 913
JO - Science
JF - Science
SN - 0036-8075
IS - 6648
ER -
