Stem Cell and developmental Biology - early embryonic lineage specification
Blegdamsvej 3B, 2200 København N, 6
Josh Brickman has a background in molecular biology and gene regulation. From a PhD in transcription he trained in developmental biology as a post-doctoral fellow, working in early mouse, and Xenopus, as well as cultivating embryonic stem cells as a model for developmental biology. He began his own lab with research projects bridging early development in multiple models systems with ES cells in a hybrid approach aimed at understanding conserved mechanisms of pluripotency and self renewal.
He currently seeks to understand how transcription factors regulate cell fate choice in ES cells and early embryos. More specifically, Professor Brickman’s and his group investigate the basis for transcriptional priming and commitment in ES cells and early in the specification of the endoderm lineage. They hope to understand the relevance of these priming events to stem and progenitor cell potency.
For more information see: http://danstem.ku.dk/people/brickman/