Looking for needles in the Plasmodial haystack

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Standard

Looking for needles in the Plasmodial haystack. / Hviid, Lars.

I: mSphere, Bind 4, Nr. 2, e00146-19, 2019.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hviid, L 2019, 'Looking for needles in the Plasmodial haystack', mSphere, bind 4, nr. 2, e00146-19. https://doi.org/10.1128/mSphere.00146-19

APA

Hviid, L. (2019). Looking for needles in the Plasmodial haystack. mSphere, 4(2), [e00146-19]. https://doi.org/10.1128/mSphere.00146-19

Vancouver

Hviid L. Looking for needles in the Plasmodial haystack. mSphere. 2019;4(2). e00146-19. https://doi.org/10.1128/mSphere.00146-19

Author

Hviid, Lars. / Looking for needles in the Plasmodial haystack. I: mSphere. 2019 ; Bind 4, Nr. 2.

Bibtex

@article{198a8b138af9406da85886ef3260eb12,
title = "Looking for needles in the Plasmodial haystack",
abstract = "Plasmodium falciparum malaria remains a globally leading infectious disease problem. Despite decades of intense investigation, an efficacious and practical vaccine offering durable protection to people living in areas with transmission of malaria parasites remains an elusive goal. Our fragmentary understanding of the mechanisms of protective immunity to the disease is a major obstacle, and the almost complete focus on a very small subset of P. falciparum proteins as vaccine candidates has left most parasite antigens essentially unexplored as targets of acquired immunity. However, with the protein microarray technology, it is now possible to interrogate the entire parasite proteome for new vaccine candidates and for markers of parasite exposure. Recent mSphere papers describe the results of such research.",
author = "Lars Hviid",
note = "Copyright {\textcopyright} 2019 Hviid.",
year = "2019",
doi = "10.1128/mSphere.00146-19",
language = "English",
volume = "4",
journal = "mSphere",
issn = "2379-5042",
publisher = "American Society for Microbiology",
number = "2",

}

RIS

TY - JOUR

T1 - Looking for needles in the Plasmodial haystack

AU - Hviid, Lars

N1 - Copyright © 2019 Hviid.

PY - 2019

Y1 - 2019

N2 - Plasmodium falciparum malaria remains a globally leading infectious disease problem. Despite decades of intense investigation, an efficacious and practical vaccine offering durable protection to people living in areas with transmission of malaria parasites remains an elusive goal. Our fragmentary understanding of the mechanisms of protective immunity to the disease is a major obstacle, and the almost complete focus on a very small subset of P. falciparum proteins as vaccine candidates has left most parasite antigens essentially unexplored as targets of acquired immunity. However, with the protein microarray technology, it is now possible to interrogate the entire parasite proteome for new vaccine candidates and for markers of parasite exposure. Recent mSphere papers describe the results of such research.

AB - Plasmodium falciparum malaria remains a globally leading infectious disease problem. Despite decades of intense investigation, an efficacious and practical vaccine offering durable protection to people living in areas with transmission of malaria parasites remains an elusive goal. Our fragmentary understanding of the mechanisms of protective immunity to the disease is a major obstacle, and the almost complete focus on a very small subset of P. falciparum proteins as vaccine candidates has left most parasite antigens essentially unexplored as targets of acquired immunity. However, with the protein microarray technology, it is now possible to interrogate the entire parasite proteome for new vaccine candidates and for markers of parasite exposure. Recent mSphere papers describe the results of such research.

U2 - 10.1128/mSphere.00146-19

DO - 10.1128/mSphere.00146-19

M3 - Journal article

C2 - 30918061

VL - 4

JO - mSphere

JF - mSphere

SN - 2379-5042

IS - 2

M1 - e00146-19

ER -

ID: 215778915