Brain expressed microRNAs implicated in schizophrenia etiology
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Brain expressed microRNAs implicated in schizophrenia etiology. / Hansen, Thomas; Olsen, Line; Lindow, Morten; Jakobsen, Klaus D; Ullum, Henrik; Jonsson, Erik; Andreassen, Ole A; Djurovic, Srdjan; Melle, Ingrid; Agartz, Ingrid; Hall, Håkan; Timm, Sally; Wang, August G; Werge, Thomas.
I: P L o S One, Bind 2, Nr. 9, 2007, s. e873.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Brain expressed microRNAs implicated in schizophrenia etiology
AU - Hansen, Thomas
AU - Olsen, Line
AU - Lindow, Morten
AU - Jakobsen, Klaus D
AU - Ullum, Henrik
AU - Jonsson, Erik
AU - Andreassen, Ole A
AU - Djurovic, Srdjan
AU - Melle, Ingrid
AU - Agartz, Ingrid
AU - Hall, Håkan
AU - Timm, Sally
AU - Wang, August G
AU - Werge, Thomas
PY - 2007
Y1 - 2007
N2 - Protein encoding genes have long been the major targets for research in schizophrenia genetics. However, with the identification of regulatory microRNAs (miRNAs) as important in brain development and function, miRNAs genes have emerged as candidates for schizophrenia-associated genetic factors. Indeed, the growing understanding of the regulatory properties and pleiotropic effects that miRNA have on molecular and cellular mechanisms, suggests that alterations in the interactions between miRNAs and their mRNA targets may contribute to phenotypic variation.
AB - Protein encoding genes have long been the major targets for research in schizophrenia genetics. However, with the identification of regulatory microRNAs (miRNAs) as important in brain development and function, miRNAs genes have emerged as candidates for schizophrenia-associated genetic factors. Indeed, the growing understanding of the regulatory properties and pleiotropic effects that miRNA have on molecular and cellular mechanisms, suggests that alterations in the interactions between miRNAs and their mRNA targets may contribute to phenotypic variation.
U2 - http://dx.doi.org/10.1371/journal.pone.0000873
DO - http://dx.doi.org/10.1371/journal.pone.0000873
M3 - Journal article
VL - 2
SP - e873
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 9
ER -
ID: 48591659