Weight loss following an intensive dietary weight loss program in obese candidates for bariatric surgery: The retrospective RNPC® cohort
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Weight loss following an intensive dietary weight loss program in obese candidates for bariatric surgery : The retrospective RNPC® cohort. / Nielsen, Mette Søndergaard; Sjödin, Anders Mikael; Fabre, Odile; Legrand, Rémy; Astrup, Arne; Hjorth, Mads Fiil.
In: Obesity Medicine, Vol. 15, 100127, 2019.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Weight loss following an intensive dietary weight loss program in obese candidates for bariatric surgery
T2 - The retrospective RNPC® cohort
AU - Nielsen, Mette Søndergaard
AU - Sjödin, Anders Mikael
AU - Fabre, Odile
AU - Legrand, Rémy
AU - Astrup, Arne
AU - Hjorth, Mads Fiil
N1 - CURIS 2019 NEXS 287
PY - 2019
Y1 - 2019
N2 - Aim: Bariatric surgery is the most effective treatment for obesity. However, less than 1% of eligible patients undergo bariatric surgery annually. Here we evaluated the weight loss effectiveness of an intensive non-surgical weight loss program in patients that would qualify for bariatric surgery. Methods: Patients eligible for bariatric surgery (n = 1460) (BMI≥40 or BMI≥35 kg/m2 plus comorbidities) who were enrolled in a dietary weight loss intervention, the RNPC® program, were compared to a cohort of bariatric surgery patients in terms of weight loss outcome. Results: The 663 patients completing the RNPC® program (35% dropout and 20% ongoing) lost 20.2 ± 11.8 kg corresponding to a reduction of 47% of the excess weight and a percentage weight loss from the initial weight of 18% after a mean period of 18.6 ± 9.1 months. Weight loss 18 months after bariatric surgery (n = 61) was 42.5 ± 15.8 kg corresponding to a reduction of 74% of excess weight and a percentage weight loss from the initial weight of 32%. Conclusion: Although bariatric surgery results in a more pronounced weight loss, a clinically important weight loss can be obtained in patients that would qualify for bariatric surgery following an intensive non-surgical weight loss program. This retrospective analysis calls for randomized trials that compare the long-term cost-effectiveness between the RNPC® program and bariatric surgery.
AB - Aim: Bariatric surgery is the most effective treatment for obesity. However, less than 1% of eligible patients undergo bariatric surgery annually. Here we evaluated the weight loss effectiveness of an intensive non-surgical weight loss program in patients that would qualify for bariatric surgery. Methods: Patients eligible for bariatric surgery (n = 1460) (BMI≥40 or BMI≥35 kg/m2 plus comorbidities) who were enrolled in a dietary weight loss intervention, the RNPC® program, were compared to a cohort of bariatric surgery patients in terms of weight loss outcome. Results: The 663 patients completing the RNPC® program (35% dropout and 20% ongoing) lost 20.2 ± 11.8 kg corresponding to a reduction of 47% of the excess weight and a percentage weight loss from the initial weight of 18% after a mean period of 18.6 ± 9.1 months. Weight loss 18 months after bariatric surgery (n = 61) was 42.5 ± 15.8 kg corresponding to a reduction of 74% of excess weight and a percentage weight loss from the initial weight of 32%. Conclusion: Although bariatric surgery results in a more pronounced weight loss, a clinically important weight loss can be obtained in patients that would qualify for bariatric surgery following an intensive non-surgical weight loss program. This retrospective analysis calls for randomized trials that compare the long-term cost-effectiveness between the RNPC® program and bariatric surgery.
KW - Bariatric surgery
KW - Diet
KW - Obesity
KW - Weight loss
UR - http://www.scopus.com/inward/record.url?scp=85070651542&partnerID=8YFLogxK
U2 - 10.1016/j.obmed.2019.100127
DO - 10.1016/j.obmed.2019.100127
M3 - Journal article
AN - SCOPUS:85070651542
VL - 15
JO - Obesity Medicine
JF - Obesity Medicine
SN - 2451-8476
M1 - 100127
ER -
ID: 227140925