Update on nephrogenic systemic fibrosis
Research output: Contribution to journal › Journal article › Research › peer-review
Gadolinium-based contrast agents were for many years considered safe, but this is no longer the case. The least stable agents may trigger the development of nephrogenic systemic fibrosis (NSF), a generalized fibrotic disorder, in renal failure patients. The use of gadodiamide and gadopentetate dimeglumine is now contraindicated in Europe and Japan in patients who have a glomerular filtration rate less than 30 mL/min/1.73 m(2), including those on dialysis. The fear of NSF, however, should not lead to an enhanced MR imaging examination being denied when there is a good clinical indication to give a gadolinium-based contrast agent
Udgivelsesdato: 2008/11
Udgivelsesdato: 2008/11
Original language | English |
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Journal | Magnetic Resonance Imaging Clinics of North America |
Volume | 16 |
Issue number | 4 |
Pages (from-to) | 551-60, vii |
ISSN | 1064-9689 |
Publication status | Published - 2008 |
ID: 13911450