Udvikling af refraktaert vasodilatorisk shock og permanent høretab efter svaer lithiumforgiftning
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Udvikling af refraktaert vasodilatorisk shock og permanent høretab efter svaer lithiumforgiftning. / Plenge, Ulla; Møller, Ann M.
In: Ugeskrift for Laeger, Vol. 170, No. 5, 28.01.2008, p. 354.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Udvikling af refraktaert vasodilatorisk shock og permanent høretab efter svaer lithiumforgiftning
AU - Plenge, Ulla
AU - Møller, Ann M
PY - 2008/1/28
Y1 - 2008/1/28
N2 - A case of severe lithium carbonate self-poisoning is described, presenting with sustained vasodilatory shock, DIC and neurologic manifestations. Lengthy and repeated haemodialysis was required to lower lithemia to non-toxic levels in accordance with which the haemodynamic instability and multi organ dysfunction ceased. The patient survived with marked loss of hearing, tinnitus and vertigo as the only sequelae. We discuss the mechanism of lithium's inhibitory effect on the phosphoinositide cascade as the possible explanation for the vasodilatory shock as well as the hearing deficiency.
AB - A case of severe lithium carbonate self-poisoning is described, presenting with sustained vasodilatory shock, DIC and neurologic manifestations. Lengthy and repeated haemodialysis was required to lower lithemia to non-toxic levels in accordance with which the haemodynamic instability and multi organ dysfunction ceased. The patient survived with marked loss of hearing, tinnitus and vertigo as the only sequelae. We discuss the mechanism of lithium's inhibitory effect on the phosphoinositide cascade as the possible explanation for the vasodilatory shock as well as the hearing deficiency.
M3 - Tidsskriftartikel
VL - 170
SP - 354
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 5
ER -
ID: 40180545