The relation of germ cells per tubule in testes, serum inhibin B and FSH in cryptorchid boys
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The relation of germ cells per tubule in testes, serum inhibin B and FSH in cryptorchid boys. / Cortes, D; Thorup, Jørgen Mogens; Hogdall, E; Norgaard-Pedersen, B; Petersen, B L; Hogdall, C.
In: Pediatric Surgery International, Vol. 23, No. 2, 01.02.2007, p. 163-9.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The relation of germ cells per tubule in testes, serum inhibin B and FSH in cryptorchid boys
AU - Cortes, D
AU - Thorup, Jørgen Mogens
AU - Hogdall, E
AU - Norgaard-Pedersen, B
AU - Petersen, B L
AU - Hogdall, C
PY - 2007/2/1
Y1 - 2007/2/1
N2 - At bilateral orchiopexy bilateral biopsies may be indicated to determine fertility potential. It is currently unknown if the serum inhibin B levels at time of orchiopexy reflect the testicular status of the bilaterally cryptorchid child. The aim of this study was to relate the results of inhibin B and FSH measurements with testicular biopsy parameters in bilateral cryptorchid boys. Included were 25 boys with bilateral cryptorchidism, median 2.5 years (9 months to 5.5 years) at surgery for bilateral cryptorchidism with simultaneous testicular biopsies, and blood sample for inhibin B and FSH. The number of spermatogonia and gonocytes was measured in 100 tubular transverse sections, the S/T and the mean-S/T of the patient was found, and expressed as percent of lowest normal value. Inhibin B and FSH were measured and related to age-specific values. Forty percent (10/25) of the patients had very low mean-S/T (mean-S/T
AB - At bilateral orchiopexy bilateral biopsies may be indicated to determine fertility potential. It is currently unknown if the serum inhibin B levels at time of orchiopexy reflect the testicular status of the bilaterally cryptorchid child. The aim of this study was to relate the results of inhibin B and FSH measurements with testicular biopsy parameters in bilateral cryptorchid boys. Included were 25 boys with bilateral cryptorchidism, median 2.5 years (9 months to 5.5 years) at surgery for bilateral cryptorchidism with simultaneous testicular biopsies, and blood sample for inhibin B and FSH. The number of spermatogonia and gonocytes was measured in 100 tubular transverse sections, the S/T and the mean-S/T of the patient was found, and expressed as percent of lowest normal value. Inhibin B and FSH were measured and related to age-specific values. Forty percent (10/25) of the patients had very low mean-S/T (mean-S/T
KW - Child, Preschool
KW - Cryptorchidism
KW - Follicle Stimulating Hormone
KW - Humans
KW - Infant
KW - Inhibins
KW - Male
KW - Seminiferous Tubules
KW - Sperm Count
KW - Spermatozoa
U2 - 10.1007/s00383-006-1839-9
DO - 10.1007/s00383-006-1839-9
M3 - Journal article
C2 - 17171380
VL - 23
SP - 163
EP - 169
JO - Pediatric Surgery International
JF - Pediatric Surgery International
SN - 0179-0358
IS - 2
ER -
ID: 34277689