The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*
Research output: Contribution to journal › Journal article › Research › peer-review
Virological failure of first-generation nonnucleoside reverse transcriptase inhibitors (NNRTIs) can compromise the efficacy of etravirine as a result of the accumulation of NNRTI resistance mutations. How quickly NNRTI resistance accumulates in patients with a delayed switch from nevirapine or efavirenz despite virological failure, when these drugs are used as a component of combination antiretroviral therapy (cART), remains unclear.
| Original language | English |
|---|---|
| Journal | HIV Medicine |
| Volume | 13 |
| Issue number | 1 |
| Pages (from-to) | 62-72 |
| Number of pages | 11 |
| ISSN | 1464-2662 |
| DOIs | |
| Publication status | Published - Jan 2012 |
ID: 48505077