Standard
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. / Baigent, Colin; Landray, Martin J; Reith, Christina; Emberson, Jonathan; Wheeler, David C; Tomson, Charles; Wanner, Christoph; Krane, Vera; Cass, Alan; Craig, Jonathan; Neal, Bruce; Jiang, Lixin; Hooi, Lai Seong; Levin, Adeera; Agodoa, Lawrence; Gaziano, Mike; Kasiske, Bertram; Walker, Robert; Massy, Ziad A; Feldt-Rasmussen, Bo; Krairittichai, Udom; Ophascharoensuk, Vuddidhej; Fellström, Bengt; Holdaas, Hallvard; Tesar, Vladimir; Wiecek, Andrzej; Grobbee, Diederick; de Zeeuw, Dick; Grönhagen-Riska, Carola; Dasgupta, Tanaji; Lewis, David; Herrington, William; Mafham, Marion; Majoni, William; Wallendszus, Karl; Grimm, Richard; Pedersen, Terje; Tobert, Jonathan; Armitage, Jane; Baxter, Alex; Bray, Christopher; Chen, Yiping; Chen, Zhengming; Hill, Michael; Knott, Carol; Parish, Sarah; Simpson, David; Sleight, Peter; Young, Alan; Collins, Rory; SHARP Investigators.
In:
Lancet, Vol. 377, No. 9784, 2011, p. 2181-92.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Baigent, C, Landray, MJ, Reith, C, Emberson, J, Wheeler, DC, Tomson, C, Wanner, C, Krane, V, Cass, A, Craig, J, Neal, B, Jiang, L, Hooi, LS, Levin, A, Agodoa, L, Gaziano, M, Kasiske, B, Walker, R, Massy, ZA
, Feldt-Rasmussen, B, Krairittichai, U, Ophascharoensuk, V, Fellström, B, Holdaas, H, Tesar, V, Wiecek, A, Grobbee, D, de Zeeuw, D, Grönhagen-Riska, C, Dasgupta, T, Lewis, D, Herrington, W, Mafham, M, Majoni, W, Wallendszus, K, Grimm, R, Pedersen, T, Tobert, J, Armitage, J, Baxter, A, Bray, C, Chen, Y, Chen, Z, Hill, M, Knott, C, Parish, S, Simpson, D, Sleight, P, Young, A, Collins, R & SHARP Investigators 2011, '
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial',
Lancet, vol. 377, no. 9784, pp. 2181-92.
https://doi.org/10.1016/S0140-6736(11)60739-3APA
Baigent, C., Landray, M. J., Reith, C., Emberson, J., Wheeler, D. C., Tomson, C., Wanner, C., Krane, V., Cass, A., Craig, J., Neal, B., Jiang, L., Hooi, L. S., Levin, A., Agodoa, L., Gaziano, M., Kasiske, B., Walker, R., Massy, Z. A., ... SHARP Investigators (2011).
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Lancet,
377(9784), 2181-92.
https://doi.org/10.1016/S0140-6736(11)60739-3Vancouver
Baigent C, Landray MJ, Reith C, Emberson J, Wheeler DC, Tomson C et al.
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Lancet. 2011;377(9784):2181-92.
https://doi.org/10.1016/S0140-6736(11)60739-3Author
Baigent, Colin ; Landray, Martin J ; Reith, Christina ; Emberson, Jonathan ; Wheeler, David C ; Tomson, Charles ; Wanner, Christoph ; Krane, Vera ; Cass, Alan ; Craig, Jonathan ; Neal, Bruce ; Jiang, Lixin ; Hooi, Lai Seong ; Levin, Adeera ; Agodoa, Lawrence ; Gaziano, Mike ; Kasiske, Bertram ; Walker, Robert ; Massy, Ziad A ; Feldt-Rasmussen, Bo ; Krairittichai, Udom ; Ophascharoensuk, Vuddidhej ; Fellström, Bengt ; Holdaas, Hallvard ; Tesar, Vladimir ; Wiecek, Andrzej ; Grobbee, Diederick ; de Zeeuw, Dick ; Grönhagen-Riska, Carola ; Dasgupta, Tanaji ; Lewis, David ; Herrington, William ; Mafham, Marion ; Majoni, William ; Wallendszus, Karl ; Grimm, Richard ; Pedersen, Terje ; Tobert, Jonathan ; Armitage, Jane ; Baxter, Alex ; Bray, Christopher ; Chen, Yiping ; Chen, Zhengming ; Hill, Michael ; Knott, Carol ; Parish, Sarah ; Simpson, David ; Sleight, Peter ; Young, Alan ; Collins, Rory ; SHARP Investigators. / The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. In: Lancet. 2011 ; Vol. 377, No. 9784. pp. 2181-92.
Bibtex
@article{356a1e089e5b49ce83bd26c7f6024d99,
title = "The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial",
abstract = "Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and the need for coronary revascularisation in people without kidney disease, but its effects in people with moderate-to-severe kidney disease are uncertain. The SHARP trial aimed to assess the efficacy and safety of the combination of simvastatin plus ezetimibe in such patients.",
author = "Colin Baigent and Landray, {Martin J} and Christina Reith and Jonathan Emberson and Wheeler, {David C} and Charles Tomson and Christoph Wanner and Vera Krane and Alan Cass and Jonathan Craig and Bruce Neal and Lixin Jiang and Hooi, {Lai Seong} and Adeera Levin and Lawrence Agodoa and Mike Gaziano and Bertram Kasiske and Robert Walker and Massy, {Ziad A} and Bo Feldt-Rasmussen and Udom Krairittichai and Vuddidhej Ophascharoensuk and Bengt Fellstr{\"o}m and Hallvard Holdaas and Vladimir Tesar and Andrzej Wiecek and Diederick Grobbee and {de Zeeuw}, Dick and Carola Gr{\"o}nhagen-Riska and Tanaji Dasgupta and David Lewis and William Herrington and Marion Mafham and William Majoni and Karl Wallendszus and Richard Grimm and Terje Pedersen and Jonathan Tobert and Jane Armitage and Alex Baxter and Christopher Bray and Yiping Chen and Zhengming Chen and Michael Hill and Carol Knott and Sarah Parish and David Simpson and Peter Sleight and Alan Young and Rory Collins and Bo Feldt-Rasmussen",
note = "Copyright {\textcopyright} 2011 Elsevier Ltd. All rights reserved.",
year = "2011",
doi = "http://dx.doi.org/10.1016/S0140-6736(11)60739-3",
language = "English",
volume = "377",
pages = "2181--92",
journal = "The Lancet",
issn = "0140-6736",
publisher = "TheLancet Publishing Group",
number = "9784",
}
RIS
TY - JOUR
T1 - The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
AU - Baigent, Colin
AU - Landray, Martin J
AU - Reith, Christina
AU - Emberson, Jonathan
AU - Wheeler, David C
AU - Tomson, Charles
AU - Wanner, Christoph
AU - Krane, Vera
AU - Cass, Alan
AU - Craig, Jonathan
AU - Neal, Bruce
AU - Jiang, Lixin
AU - Hooi, Lai Seong
AU - Levin, Adeera
AU - Agodoa, Lawrence
AU - Gaziano, Mike
AU - Kasiske, Bertram
AU - Walker, Robert
AU - Massy, Ziad A
AU - Feldt-Rasmussen, Bo
AU - Krairittichai, Udom
AU - Ophascharoensuk, Vuddidhej
AU - Fellström, Bengt
AU - Holdaas, Hallvard
AU - Tesar, Vladimir
AU - Wiecek, Andrzej
AU - Grobbee, Diederick
AU - de Zeeuw, Dick
AU - Grönhagen-Riska, Carola
AU - Dasgupta, Tanaji
AU - Lewis, David
AU - Herrington, William
AU - Mafham, Marion
AU - Majoni, William
AU - Wallendszus, Karl
AU - Grimm, Richard
AU - Pedersen, Terje
AU - Tobert, Jonathan
AU - Armitage, Jane
AU - Baxter, Alex
AU - Bray, Christopher
AU - Chen, Yiping
AU - Chen, Zhengming
AU - Hill, Michael
AU - Knott, Carol
AU - Parish, Sarah
AU - Simpson, David
AU - Sleight, Peter
AU - Young, Alan
AU - Collins, Rory
AU - SHARP Investigators
N1 - Copyright © 2011 Elsevier Ltd. All rights reserved.
PY - 2011
Y1 - 2011
N2 - Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and the need for coronary revascularisation in people without kidney disease, but its effects in people with moderate-to-severe kidney disease are uncertain. The SHARP trial aimed to assess the efficacy and safety of the combination of simvastatin plus ezetimibe in such patients.
AB - Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and the need for coronary revascularisation in people without kidney disease, but its effects in people with moderate-to-severe kidney disease are uncertain. The SHARP trial aimed to assess the efficacy and safety of the combination of simvastatin plus ezetimibe in such patients.
U2 - http://dx.doi.org/10.1016/S0140-6736(11)60739-3
DO - http://dx.doi.org/10.1016/S0140-6736(11)60739-3
M3 - Journal article
VL - 377
SP - 2181
EP - 2192
JO - The Lancet
JF - The Lancet
SN - 0140-6736
IS - 9784
ER -
