The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder. / Faurholt-Jepsen, M.; Frost, M.; Christensen, E.M.; Bardram, J E; Vinberg, M; Kessing, L.V.

In: Acta Psychiatrica Scandinavica, Vol. 139, No. 5, 2019, p. 443-453.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Faurholt-Jepsen, M, Frost, M, Christensen, EM, Bardram, JE, Vinberg, M & Kessing, LV 2019, 'The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder', Acta Psychiatrica Scandinavica, vol. 139, no. 5, pp. 443-453. https://doi.org/10.1111/acps.13021

APA

Faurholt-Jepsen, M., Frost, M., Christensen, E. M., Bardram, J. E., Vinberg, M., & Kessing, L. V. (2019). The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder. Acta Psychiatrica Scandinavica, 139(5), 443-453. https://doi.org/10.1111/acps.13021

Vancouver

Faurholt-Jepsen M, Frost M, Christensen EM, Bardram JE, Vinberg M, Kessing LV. The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder. Acta Psychiatrica Scandinavica. 2019;139(5):443-453. https://doi.org/10.1111/acps.13021

Author

Faurholt-Jepsen, M. ; Frost, M. ; Christensen, E.M. ; Bardram, J E ; Vinberg, M ; Kessing, L.V. / The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder. In: Acta Psychiatrica Scandinavica. 2019 ; Vol. 139, No. 5. pp. 443-453.

Bibtex

@article{89eead49bef44720b24170a130f8a09a,
title = "The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder",
abstract = "OBJECTIVE: To (i) validate patient-evaluated mixed symptoms and irritability measured using smartphones against clinical evaluations; (ii) investigate associations between mixed symptoms and irritability with stress, quality of life and functioning, respectively, in patients with bipolar disorder.METHODS: A total of 84 patients with bipolar disorder used a smartphone-based system for daily evaluation of mixed symptoms and irritability for nine months. Clinically evaluated symptoms, stress, quality of life and clinically rated functioning were collected multiple times during follow-up.RESULTS: Patients presented mild affective symptoms. Patient-reported mixed symptoms and irritability correlated with clinical evaluations. In analyses including confounding factors there was a statistically significant association between both mixed symptoms and irritability and stress (P < 0.0001) and between irritability and both quality of life and functioning (P < 0.0001) respectively. There was no association between mixed mood and both quality of life and functioning.CONCLUSION: Mixed symptoms and irritability can be validly self-reported using smartphones in patients with bipolar disorder. Mixed symptoms and irritability are associated with increased stress even during full or partial remission. Irritability is associated with decreased quality of life and functioning. The findings emphasize the clinical importance of identifying inter-episodic symptoms including irritability pointing towards smartphones as a valid tool.",
author = "M. Faurholt-Jepsen and M. Frost and E.M. Christensen and Bardram, {J E} and M Vinberg and L.V. Kessing",
year = "2019",
doi = "10.1111/acps.13021",
language = "English",
volume = "139",
pages = "443--453",
journal = "Acta Psychiatrica Scandinavica",
issn = "0001-690X",
publisher = "Wiley",
number = "5",

}

RIS

TY - JOUR

T1 - The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder

AU - Faurholt-Jepsen, M.

AU - Frost, M.

AU - Christensen, E.M.

AU - Bardram, J E

AU - Vinberg, M

AU - Kessing, L.V.

PY - 2019

Y1 - 2019

N2 - OBJECTIVE: To (i) validate patient-evaluated mixed symptoms and irritability measured using smartphones against clinical evaluations; (ii) investigate associations between mixed symptoms and irritability with stress, quality of life and functioning, respectively, in patients with bipolar disorder.METHODS: A total of 84 patients with bipolar disorder used a smartphone-based system for daily evaluation of mixed symptoms and irritability for nine months. Clinically evaluated symptoms, stress, quality of life and clinically rated functioning were collected multiple times during follow-up.RESULTS: Patients presented mild affective symptoms. Patient-reported mixed symptoms and irritability correlated with clinical evaluations. In analyses including confounding factors there was a statistically significant association between both mixed symptoms and irritability and stress (P < 0.0001) and between irritability and both quality of life and functioning (P < 0.0001) respectively. There was no association between mixed mood and both quality of life and functioning.CONCLUSION: Mixed symptoms and irritability can be validly self-reported using smartphones in patients with bipolar disorder. Mixed symptoms and irritability are associated with increased stress even during full or partial remission. Irritability is associated with decreased quality of life and functioning. The findings emphasize the clinical importance of identifying inter-episodic symptoms including irritability pointing towards smartphones as a valid tool.

AB - OBJECTIVE: To (i) validate patient-evaluated mixed symptoms and irritability measured using smartphones against clinical evaluations; (ii) investigate associations between mixed symptoms and irritability with stress, quality of life and functioning, respectively, in patients with bipolar disorder.METHODS: A total of 84 patients with bipolar disorder used a smartphone-based system for daily evaluation of mixed symptoms and irritability for nine months. Clinically evaluated symptoms, stress, quality of life and clinically rated functioning were collected multiple times during follow-up.RESULTS: Patients presented mild affective symptoms. Patient-reported mixed symptoms and irritability correlated with clinical evaluations. In analyses including confounding factors there was a statistically significant association between both mixed symptoms and irritability and stress (P < 0.0001) and between irritability and both quality of life and functioning (P < 0.0001) respectively. There was no association between mixed mood and both quality of life and functioning.CONCLUSION: Mixed symptoms and irritability can be validly self-reported using smartphones in patients with bipolar disorder. Mixed symptoms and irritability are associated with increased stress even during full or partial remission. Irritability is associated with decreased quality of life and functioning. The findings emphasize the clinical importance of identifying inter-episodic symptoms including irritability pointing towards smartphones as a valid tool.

U2 - 10.1111/acps.13021

DO - 10.1111/acps.13021

M3 - Journal article

C2 - 30865288

VL - 139

SP - 443

EP - 453

JO - Acta Psychiatrica Scandinavica

JF - Acta Psychiatrica Scandinavica

SN - 0001-690X

IS - 5

ER -

ID: 238001476