The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators: A histochemical study

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The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators : A histochemical study. / Kirkeby, S.

In: Histochemistry, Vol. 48, No. 1, 1976, p. 51-60.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Kirkeby, S 1976, 'The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators: A histochemical study', Histochemistry, vol. 48, no. 1, pp. 51-60. https://doi.org/10.1007/BF00489716

APA

Kirkeby, S. (1976). The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators: A histochemical study. Histochemistry, 48(1), 51-60. https://doi.org/10.1007/BF00489716

Vancouver

Kirkeby S. The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators: A histochemical study. Histochemistry. 1976;48(1):51-60. https://doi.org/10.1007/BF00489716

Author

Kirkeby, S. / The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators : A histochemical study. In: Histochemistry. 1976 ; Vol. 48, No. 1. pp. 51-60.

Bibtex

@article{b4143f90eeda11ddbf70000ea68e967b,
title = "The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators: A histochemical study",
abstract = "The action of various inhibitors and activators upon esterase activity in the thyroid epithelial cells is demonstrated. The agents used were triorthocresylphosphate (TOCP), parachloromercuribenzoate (PCMB), Arsanillic acid, p-nitrophenyl dimethyl carbamate and bis p-nitrophenyl phosphate. TOCP was found to inhibit selectively the activity in the follicle cells proper when alpha naphthyl acetate was used as a substrate. Arsanillic acid (0,001 M) activated the follicle cells proper selectively, but if the concentration was raised to 0,01 M the effect was that of inhibition while the activity in the para-, inter- and intrafollicular cells was unchanged. The results obtained are related to previous biochemical and histochemical observations and the nature of esterases in the thyroid is discussed.",
author = "S. Kirkeby",
note = "Keywords: Acetylesterase; Animals; Carbamates; Chloromercuribenzoates; Esterases; Guinea Pigs; Histocytochemistry; Thyroid Gland; Tritolyl Phosphates",
year = "1976",
doi = "10.1007/BF00489716",
language = "English",
volume = "48",
pages = "51--60",
journal = "Histochemistry",
issn = "0301-5564",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - The activity of non-specific esterase in the thyroid epithelial cells of the guinea pig as influenced by various inhibitors and activators

T2 - A histochemical study

AU - Kirkeby, S.

N1 - Keywords: Acetylesterase; Animals; Carbamates; Chloromercuribenzoates; Esterases; Guinea Pigs; Histocytochemistry; Thyroid Gland; Tritolyl Phosphates

PY - 1976

Y1 - 1976

N2 - The action of various inhibitors and activators upon esterase activity in the thyroid epithelial cells is demonstrated. The agents used were triorthocresylphosphate (TOCP), parachloromercuribenzoate (PCMB), Arsanillic acid, p-nitrophenyl dimethyl carbamate and bis p-nitrophenyl phosphate. TOCP was found to inhibit selectively the activity in the follicle cells proper when alpha naphthyl acetate was used as a substrate. Arsanillic acid (0,001 M) activated the follicle cells proper selectively, but if the concentration was raised to 0,01 M the effect was that of inhibition while the activity in the para-, inter- and intrafollicular cells was unchanged. The results obtained are related to previous biochemical and histochemical observations and the nature of esterases in the thyroid is discussed.

AB - The action of various inhibitors and activators upon esterase activity in the thyroid epithelial cells is demonstrated. The agents used were triorthocresylphosphate (TOCP), parachloromercuribenzoate (PCMB), Arsanillic acid, p-nitrophenyl dimethyl carbamate and bis p-nitrophenyl phosphate. TOCP was found to inhibit selectively the activity in the follicle cells proper when alpha naphthyl acetate was used as a substrate. Arsanillic acid (0,001 M) activated the follicle cells proper selectively, but if the concentration was raised to 0,01 M the effect was that of inhibition while the activity in the para-, inter- and intrafollicular cells was unchanged. The results obtained are related to previous biochemical and histochemical observations and the nature of esterases in the thyroid is discussed.

U2 - 10.1007/BF00489716

DO - 10.1007/BF00489716

M3 - Journal article

C2 - 993058

VL - 48

SP - 51

EP - 60

JO - Histochemistry

JF - Histochemistry

SN - 0301-5564

IS - 1

ER -

ID: 10026761