Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications. / Bjerrum, Jacob Tveiten; Nielsen, Ole H; Wang, Yulan L; Olsen, Jørgen.

In: Nature Clinical Practice Gastroenterology & Hepatology, Vol. 5, No. 6, 2008, p. 332-43.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bjerrum, JT, Nielsen, OH, Wang, YL & Olsen, J 2008, 'Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.', Nature Clinical Practice Gastroenterology & Hepatology, vol. 5, no. 6, pp. 332-43. https://doi.org/10.1038/ncpgasthep1125

APA

Bjerrum, J. T., Nielsen, O. H., Wang, Y. L., & Olsen, J. (2008). Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications. Nature Clinical Practice Gastroenterology & Hepatology, 5(6), 332-43. https://doi.org/10.1038/ncpgasthep1125

Vancouver

Bjerrum JT, Nielsen OH, Wang YL, Olsen J. Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications. Nature Clinical Practice Gastroenterology & Hepatology. 2008;5(6):332-43. https://doi.org/10.1038/ncpgasthep1125

Author

Bjerrum, Jacob Tveiten ; Nielsen, Ole H ; Wang, Yulan L ; Olsen, Jørgen. / Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications. In: Nature Clinical Practice Gastroenterology & Hepatology. 2008 ; Vol. 5, No. 6. pp. 332-43.

Bibtex

@article{3a4b1f3084bd11dd81b0000ea68e967b,
title = "Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.",
abstract = "Metabonomics-the study of metabolic changes in an integrated biologic system-is an emerging field. This discipline joins the other 'omics' (genomics, transcriptomics and proteomics) to give rise to a comprehensive, systems-biology approach to the evaluation of holistic in vivo function. Metabonomics, especially when based on nuclear magnetic resonance spectroscopy, has the potential to identify biomarkers and prognostic factors, enhance clinical diagnosis, and expand hypothesis generation. As a consequence, the use of metabonomics has been extensively explored in the past decade, and applied successfully to the study of human diseases, toxicology, microbes, nutrition, and plant biology. This Review introduces the basic principles of nuclear magnetic resonance spectroscopy and commonly used tools for multivariate data analysis, before considering the applications and future potential of metabonomics in basic and clinical research, with emphasis on applications in the field of gastroenterology.",
author = "Bjerrum, {Jacob Tveiten} and Nielsen, {Ole H} and Wang, {Yulan L} and J{\o}rgen Olsen",
note = "Keywords: Gastroenterology; Gastrointestinal Diseases; Humans; Magnetic Resonance Spectroscopy; Metabolism",
year = "2008",
doi = "10.1038/ncpgasthep1125",
language = "English",
volume = "5",
pages = "332--43",
journal = "Nature Clinical Practice Gastroenterology & Hepatology",
issn = "1743-4378",
publisher = "nature publishing group",
number = "6",

}

RIS

TY - JOUR

T1 - Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.

AU - Bjerrum, Jacob Tveiten

AU - Nielsen, Ole H

AU - Wang, Yulan L

AU - Olsen, Jørgen

N1 - Keywords: Gastroenterology; Gastrointestinal Diseases; Humans; Magnetic Resonance Spectroscopy; Metabolism

PY - 2008

Y1 - 2008

N2 - Metabonomics-the study of metabolic changes in an integrated biologic system-is an emerging field. This discipline joins the other 'omics' (genomics, transcriptomics and proteomics) to give rise to a comprehensive, systems-biology approach to the evaluation of holistic in vivo function. Metabonomics, especially when based on nuclear magnetic resonance spectroscopy, has the potential to identify biomarkers and prognostic factors, enhance clinical diagnosis, and expand hypothesis generation. As a consequence, the use of metabonomics has been extensively explored in the past decade, and applied successfully to the study of human diseases, toxicology, microbes, nutrition, and plant biology. This Review introduces the basic principles of nuclear magnetic resonance spectroscopy and commonly used tools for multivariate data analysis, before considering the applications and future potential of metabonomics in basic and clinical research, with emphasis on applications in the field of gastroenterology.

AB - Metabonomics-the study of metabolic changes in an integrated biologic system-is an emerging field. This discipline joins the other 'omics' (genomics, transcriptomics and proteomics) to give rise to a comprehensive, systems-biology approach to the evaluation of holistic in vivo function. Metabonomics, especially when based on nuclear magnetic resonance spectroscopy, has the potential to identify biomarkers and prognostic factors, enhance clinical diagnosis, and expand hypothesis generation. As a consequence, the use of metabonomics has been extensively explored in the past decade, and applied successfully to the study of human diseases, toxicology, microbes, nutrition, and plant biology. This Review introduces the basic principles of nuclear magnetic resonance spectroscopy and commonly used tools for multivariate data analysis, before considering the applications and future potential of metabonomics in basic and clinical research, with emphasis on applications in the field of gastroenterology.

U2 - 10.1038/ncpgasthep1125

DO - 10.1038/ncpgasthep1125

M3 - Journal article

C2 - 18431374

VL - 5

SP - 332

EP - 343

JO - Nature Clinical Practice Gastroenterology & Hepatology

JF - Nature Clinical Practice Gastroenterology & Hepatology

SN - 1743-4378

IS - 6

ER -

ID: 6093307