Symptom-Specific Hospital Contacts in 12–18-Year-Olds Vaccinated against COVID-19: A Danish Register-Based Cohort Study
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Symptom-Specific Hospital Contacts in 12–18-Year-Olds Vaccinated against COVID-19 : A Danish Register-Based Cohort Study. / Berg, Selina Kikkenborg; Wallach-Kildemoes, Helle; Rasmussen, Line Ryberg; Nygaard, Ulrikka; Birk, Nina Marie; Bundgaard, Henning; Ersbøll, Annette Kjær; Thygesen, Lau Caspar; Nielsen, Susanne Dam; Christensen, Anne Vinggaard.
In: Vaccines, Vol. 11, No. 6, 1049, 06.2023.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Symptom-Specific Hospital Contacts in 12–18-Year-Olds Vaccinated against COVID-19
T2 - A Danish Register-Based Cohort Study
AU - Berg, Selina Kikkenborg
AU - Wallach-Kildemoes, Helle
AU - Rasmussen, Line Ryberg
AU - Nygaard, Ulrikka
AU - Birk, Nina Marie
AU - Bundgaard, Henning
AU - Ersbøll, Annette Kjær
AU - Thygesen, Lau Caspar
AU - Nielsen, Susanne Dam
AU - Christensen, Anne Vinggaard
N1 - Publisher Copyright: © 2023 by the authors.
PY - 2023/6
Y1 - 2023/6
N2 - In this register-based real-life cohort study, changes in symptom-specific hospital contacts among 12–18-year-olds following two doses of the BNT162b2 COVID-19 vaccine compared to unvaccinated peers were investigated. Using national register data, vaccinated and unvaccinated adolescents were sex and age-matched each week during the inclusion period from May to September 2021. Symptom-specific hospital contacts covering ICD-10 R diagnoses were assessed before first the vaccine dose and after the second vaccine dose. Taking previous rates of symptom-specific hospital contacts into account, differences between vaccinated and unvaccinated adolescents were found. For some hospital contacts, higher rates were seen among the vaccinated, and for others, higher rates were seen among the unvaccinated. Unspecific cognition symptoms may be important to monitor in vaccinated girls, and likewise for throat and chest pain in vaccinated boys within the first months post-vaccination. In perspective, symptom-specific hospital contacts after vaccination against COVID-19 must be assessed by taking the risk of infection and symptoms following COVID-19 infection into account.
AB - In this register-based real-life cohort study, changes in symptom-specific hospital contacts among 12–18-year-olds following two doses of the BNT162b2 COVID-19 vaccine compared to unvaccinated peers were investigated. Using national register data, vaccinated and unvaccinated adolescents were sex and age-matched each week during the inclusion period from May to September 2021. Symptom-specific hospital contacts covering ICD-10 R diagnoses were assessed before first the vaccine dose and after the second vaccine dose. Taking previous rates of symptom-specific hospital contacts into account, differences between vaccinated and unvaccinated adolescents were found. For some hospital contacts, higher rates were seen among the vaccinated, and for others, higher rates were seen among the unvaccinated. Unspecific cognition symptoms may be important to monitor in vaccinated girls, and likewise for throat and chest pain in vaccinated boys within the first months post-vaccination. In perspective, symptom-specific hospital contacts after vaccination against COVID-19 must be assessed by taking the risk of infection and symptoms following COVID-19 infection into account.
KW - children and adolescents
KW - COVID-19
KW - symptoms
KW - vaccine
U2 - 10.3390/vaccines11061049
DO - 10.3390/vaccines11061049
M3 - Journal article
C2 - 37376438
AN - SCOPUS:85163740470
VL - 11
JO - Vaccines
JF - Vaccines
SN - 2076-393X
IS - 6
M1 - 1049
ER -
ID: 393846258