Significance of incisional biopsy in breast carcinoma: Results from a clinical trial with intended excisional biopsy
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Significance of incisional biopsy in breast carcinoma : Results from a clinical trial with intended excisional biopsy. / Watt-Boolsen, S.; Ottesen, G.; Andersen, J. A.; Bayer, T.; Jespersen, N. C. B.; Keiding, N.; Mouridsen, H. T.; Dombernowsky, P.; Blichert-Toft, M.
In: European Journal of Surgical Oncology, Vol. 15, No. 1, 1989, p. 33-37.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Significance of incisional biopsy in breast carcinoma
T2 - Results from a clinical trial with intended excisional biopsy
AU - Watt-Boolsen, S.
AU - Ottesen, G.
AU - Andersen, J. A.
AU - Bayer, T.
AU - Jespersen, N. C. B.
AU - Keiding, N.
AU - Mouridsen, H. T.
AU - Dombernowsky, P.
AU - Blichert-Toft, M.
PY - 1989
Y1 - 1989
N2 - The recurrence-free survival rates (RFS) after one-stage mastectomy and partial axillary dissection in 1242 low risk breast cancer patients with invasive ductal carcinoma with or without residual cancer tissue (RCT) in the wall of the biopsy cavity were compared. RFS was significantly lower in patients with RCT (RCT-positive) whether premenopausal (n = 416) or postmenopausal (n = 826). By applying the Cox multivariate analysis on RCT and various known prognostic criteria, the incidence rates for RCT-positive patients relative to RCT-negative patients were estimated. The relative risk by RCT-positivity was in the order of 1.45, indicating that RCT is an independent risk factor contributing an increased risk of recurrence of about 45%.
AB - The recurrence-free survival rates (RFS) after one-stage mastectomy and partial axillary dissection in 1242 low risk breast cancer patients with invasive ductal carcinoma with or without residual cancer tissue (RCT) in the wall of the biopsy cavity were compared. RFS was significantly lower in patients with RCT (RCT-positive) whether premenopausal (n = 416) or postmenopausal (n = 826). By applying the Cox multivariate analysis on RCT and various known prognostic criteria, the incidence rates for RCT-positive patients relative to RCT-negative patients were estimated. The relative risk by RCT-positivity was in the order of 1.45, indicating that RCT is an independent risk factor contributing an increased risk of recurrence of about 45%.
UR - http://www.scopus.com/inward/record.url?scp=0024593218&partnerID=8YFLogxK
M3 - Journal article
C2 - 2537237
AN - SCOPUS:0024593218
VL - 15
SP - 33
EP - 37
JO - European Journal of Surgical Oncology
JF - European Journal of Surgical Oncology
SN - 0748-7983
IS - 1
ER -
ID: 202331414